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Table 1 Subject group characteristics—control (CTRL), diagnosed (Dx), and symptomatic (Sx)

From: Single-cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosis

  CTRL Dx Sx Total P value (CTRL vs Dx)
Age (years) (mean ± SD) 33.4 ± 5.4 35.2 ± 4.4 32.3 ± 8.2 33.6 ± 6.3 0.42
BMI (kg/m2) (mean ± SD) 24.2 ± 7.1 28.4 ± 5.4 26.8 ± 7.6 26.5 ± 6.8 0.15
Age at menarche (years) (mean ± SD) 12.0 ± 0.9 11.6 ± 1.6 12.6 ± 1.7 12.0 ± 1.5 0.51
Race/ethnicity      0.34
 Caucasian 7/9 (78%) 0/11 (91%) 13/13 (100%) 30/33 (91%)  
 Black 1/9 (11%) 0/11 (0%) 0/13 (0%) 1/33 (3%)  
 Mixed 1/9 (11%) 0/11 (0%) 0/13 (0%) 1/33 (3%)  
 Other 0/9 (0%) 1/11 (9%) 0/13 (0%) 1/33 (3%)  
 Hispanic   0/9 (0%) 0/11 (0%) 1/13 (8%)  
Typical cycle length (days)      0.52
 21–25 days 0/9 (0%) 1/11 (9%) 3/13 (23%) 4/33 (12%)  
 26–31 days 8/9 (89%) 7/11 (64%) 8/13 (62%) 23/33 (70%)  
 32–39 days 1/9 (11%) 2/11 (18%) 2/13 (15%) 5/33 (15%)  
 > 40 days 0/9 (0%) 1/11 (9%) 0/13 (0%) 1/33 (3%)  
Typical bleed time (days)      0.36
 < 3 days 0/9 (0%) 2/11 (18%) 0/13 (0%) 2/33 (6%)  
 3–5 days 5/9 (56%) 6/11 (55%) 8/13 (62%) 19/33 (58%)  
 6–8 days 4/9 (44%) 3/11 (23%) 5/13 (38%) 12/33 (36%)  
Typical flow      0.96
 Light 1/9 (11%) 1/11 (9%) 0/13 (0%) 2/33 (6%)  
 Moderate 2/9 (22%) 2/11 (18%) 3/13 (23%) 7/33 (21%)  
 Moderately heavy 3/9 (33%) 5/11 (45%) 9/13 (69%) 17/33 (52%)  
 Heavy 3/9 (33%) 3/11 (23%) 1/13 (8%) 7/33 (21%)  
Hormone use      0.35
 Yes 0/9 (0%) 1/11 (9%)+ 1/13 (8%) 2/33 (6%)  
Pain in this cycle      0.06
 Yes 5/9 (56%) 10/11 (91%) 13/13 (100%)* 28/33 (85%)  
 None 4/9 (44%) 1/11 (9%) 0/13 (0%) 5/33 (15%)  
 Mild 2/9 (22%) 3/11 (23%) 3/13 (23%) 8/33 (24%)  
 Moderate 3/9 (33%) 6/11 (55%) 4/13 (31%) 13/33 (40%)  
 Severe 0/9 (0%) 1/11 (9%) 6/13 (46%) 7/33 (21%)  
Pain medication in this cycle (Midol, Advil, Tylenol, Naproxen, Hydromorphone 2 mg/Baclofen/diazepam/Ketamine 8/10/15 mg)
 Yes 1/9 (11%) 6/11 (55%) 10/13 (77%) 17/33 (52%)  
  1. No comparisons of CTRL vs. Sx were significant for the above characteristics, except pain (yes/no): *p = 0.008; +one patient used 200mg of progesterone (Prometrium vaginal suppositories) 2 days prior to menses