Table 1 Subject group characteristics—control (CTRL), diagnosed (Dx), and symptomatic (Sx)

Age (years) (mean ± SD)

33.4 ± 5.4

35.2 ± 4.4

32.3 ± 8.2

33.6 ± 6.3

0.42

BMI (kg/m²) (mean ± SD)

24.2 ± 7.1

28.4 ± 5.4

26.8 ± 7.6

26.5 ± 6.8

0.15

Age at menarche (years) (mean ± SD)

12.0 ± 0.9

11.6 ± 1.6

12.6 ± 1.7

12.0 ± 1.5

0.51

Race/ethnicity

0.34

 Caucasian

7/9 (78%)

0/11 (91%)

13/13 (100%)

30/33 (91%)

 Black

1/9 (11%)

0/11 (0%)

0/13 (0%)

1/33 (3%)

 Mixed

1/9 (11%)

0/11 (0%)

0/13 (0%)

1/33 (3%)

 Other

0/9 (0%)

1/11 (9%)

0/13 (0%)

1/33 (3%)

 Hispanic

0/9 (0%)

0/11 (0%)

1/13 (8%)

Typical cycle length (days)

0.52

 21–25 days

0/9 (0%)

1/11 (9%)

3/13 (23%)

4/33 (12%)

 26–31 days

8/9 (89%)

7/11 (64%)

8/13 (62%)

23/33 (70%)

 32–39 days

1/9 (11%)

2/11 (18%)

2/13 (15%)

5/33 (15%)

 > 40 days

0/9 (0%)

1/11 (9%)

0/13 (0%)

1/33 (3%)

Typical bleed time (days)

0.36

 < 3 days

0/9 (0%)

2/11 (18%)

0/13 (0%)

2/33 (6%)

 3–5 days

5/9 (56%)

6/11 (55%)

8/13 (62%)

19/33 (58%)

 6–8 days

4/9 (44%)

3/11 (23%)

5/13 (38%)

12/33 (36%)

Typical flow

0.96

 Light

1/9 (11%)

1/11 (9%)

0/13 (0%)

2/33 (6%)

 Moderate

2/9 (22%)

2/11 (18%)

3/13 (23%)

7/33 (21%)

 Moderately heavy

3/9 (33%)

5/11 (45%)

9/13 (69%)

17/33 (52%)

 Heavy

3/9 (33%)

3/11 (23%)

1/13 (8%)

7/33 (21%)

Hormone use

0.35

 Yes

0/9 (0%)

1/11 (9%)⁺

1/13 (8%)

2/33 (6%)

Pain in this cycle

0.06

 Yes

5/9 (56%)

10/11 (91%)

13/13 (100%)*

28/33 (85%)

 None

4/9 (44%)

1/11 (9%)

0/13 (0%)

5/33 (15%)

 Mild

2/9 (22%)

3/11 (23%)

3/13 (23%)

8/33 (24%)

 Moderate

3/9 (33%)

6/11 (55%)

4/13 (31%)

13/33 (40%)

 Severe

0/9 (0%)

1/11 (9%)

6/13 (46%)

7/33 (21%)

 Yes

1/9 (11%)

6/11 (55%)

10/13 (77%)

17/33 (52%)