CT-based | Hazard ratio (95% confidence interval) |
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Model 1 (N = 2139) | Model 2 (N = 2139) | Model 3a (N = 1297) | Model 4b (N = 1297) |
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Liver fat | 1.10 (0.94–1.28) | 1.06 (0.90–1.25) | 1.08 (0.88–1.32) | 1.05 (0.86–1.29) |
Epicardial fat | 1.31 (1.13–1.51) | 1.27 (1.09–1.48) | 1.16 (0.95–1.42) | 1.09 (0.87–1.38) |
- Values are shown as hazard ratios and 95% confidence interval per 1 standard deviation increase of corresponding fat depots
- Abbreviations CTÂ computed tomography
- Model 1 was adjusted for sex and age
- Model 2 was additionally adjusted for high-density lipoprotein cholesterol, total cholesterol, smoking, total alcohol intake, lipid-lowering medication and cardiac medication and history of hypertension, left ventricular hypertrophy, diabetes mellitus, heart failure, and coronary heart disease
- aModel 3: Model 2 + total lean mass (in a sub-sample of 1297 participants with available DXA measurements)
- bModel 4: Model 2 + total fat mass (in a sub-sample of 1297 participants with available DXA measurements)