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Table 6 Associations between the biomarkers and both the lifestyle score and the mental health and well-being outcomes

From: A healthy lifestyle is positively associated with mental health and well-being and core markers in ageing

Lifestyle score/mental health and well-being outcome

TL

mtDNAc

% difference

95% CI

p-value

% difference

95% CI

p-value

Lifestyle score

1.74

0.11, 3.40

0.037

4.07

2.01, 6.17

0.00012

Psychological distress

 − 0.12

 − 3.04, 2.88

0.94

 − 2.29

 − 5.82, 1.36

0.21

Severe psychological distress

0.21

 − 3.39, 3.94

0.91

 − 4.62

 − 8.85, − 0.20

0.041

Suboptimal vitality

 − 3.26

 − 7.46, 1.12

0.14

 − 2.37

 − 7.62, 3.17

0.39

Low life satisfaction

0.20

 − 4.18, 4.79

0.93

 − 2.00

 − 7.30, 3.59

0.47

Very bad to fair self-perceived health

 − 0.79

 − 4.36, 2.90

0.67

 − 2.53

 − 6.87, 2.00

0.27

Depressive disorder

2.54

 − 2.41, 7.73

0.32

2.84

 − 3.28, 9.36

0.37

Generalised anxiety disorder

0.56

 − 3.88, 5.20

0.81

2.05

 − 3.52, 7.94

0.48

Suicidal ideation

0.73

 − 5.44, 7.31

0.82

 − 7.83

 − 14.77, − 0.34

0.041

  1. Difference (%) in relative telomere length (TL) and mitochondrial DNA content (mtDNAc) (with 95% CI) (1) for a one-point increment in the lifestyle score or (2) when having a mental health disorder or condition compared with the healthy group. Analyses were adjusted for age, sex, region, highest educational level in the household, household composition, country of birth and day of sample collection