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Table 2 Risk of adverse clinical events and relationship with ABC pathway, according to cluster (n=6091)

From: Clinical complexity and impact of the ABC (Atrial fibrillation Better Care) pathway in patients with atrial fibrillation: a report from the ESC-EHRA EURObservational Research Programme in AF General Long-Term Registry

  High clinical complexity cluster
N=2398
Moderate clinical complexity cluster
N=3693
All-cause death, n (%) 363 (15.1) 172 (4.6)
 ABC adherent, vs. non-adherent 0.74 [0.56–0.98] 0.83 [0.59–1.16]
 1 ABC criteria, vs. 0 0.54 [0.34–0.84] 0.42 [0.18–1.01]
 2 ABC criteria, vs. 0 0.36 [0.23–0.56] 0.32 [0.14–0.73]
 3 ABC criteria, vs. 0 0.32 [0.20–0.52] 0.29 [0.12–0.69]
 For each criteria 0.71 [0.62–0.82] 0.79 [0.64–0.96]
 2–3 ABC criteria, vs. 0–1 0.60 [0.48–0.75] 0.67 [0.47–0.96]
MACE, n (%) 375 (15.6) 203 (5.5)
 ABC adherent, vs. non-adherent 0.80 [0.60–1.08] 0.58 [0.39–0.85]
 1 ABC criteria, vs. 0 0.63 [0.36–1.09] 0.62 [0.24–1.60]
 2 ABC criteria, vs. 0 0.45 [0.26–0.78] 0.41 [0.16–1.03]
 3 ABC criteria, vs. 0 0.41 [0.23–0.74] 0.27 [0.10–0.70]
 For each criteria 0.77 [0.66–0.90] 0.65 [0.53–0.81]
 2–3 ABC criteria, vs. 0–1 0.66 [0.51–0.85] 0.55 [0.38–0.79]
Composite outcome, n (%) 554 (23.1) 320 (8.7)
 ABC adherent, vs. non-adherent 0.76 [0.60–0.96] 0.70 [0.54–0.92]
 1 ABC criteria, vs. 0 0.62 [0.40–0.94] 0.65 [0.29–1.42]
 2 ABC criteria, vs. 0 0.44 [0.29–0.66] 0.46 [0.21–1.00]
 3 ABC criteria, vs. 0 0.38 [0.25–0.60] 0.36 [0.16–0.80]
 For each criteria 0.75 [0.66–0.85] 0.74 [0.63–0.87]
 2–3 ABC criteria, vs. 0–1 0.64 [0.53–0.78] 0.63 [0.48–0.84]
  1. Legend: HR [95%CI] adjusted for age, sex, type of AF, hypertension, diabetes, congestive heart failure, coronary artery disease, peripheral artery disease and previous thromboembolism