Fig. 3

Primary meta-analyses. A The log2 difference between phases (log2-pg/mL of the luteal phase minus log2-pg/mL of the follicular phase). B The logistic difference between phases (log-odds of proportion detectable in luteal vs. follicular phase). Each row represents a different immune mediator, with the symbols showing the mean and the lines showing the 95% confidence intervals. Gray symbols indicate individual studies and blue the meta-estimates as determined by inverse-variance pooling random effects models. Filled symbols indicate p < 0.05 while open symbols indicate p > 0.05. Positive numbers indicate higher during the luteal phase (relative to the follicular phase), while negative numbers indicate lower during the luteal phase (relative to the follicular phase). Symbol shape and shade of blue indicate the GRADE strength of evidence