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Table 2 Post-mortem and non-post-mortem causes of death

From: Post-mortem examination of high mortality in patients with heart failure and atrial fibrillation

Mode of death

Post-mortem performed (n = 186)

Post-mortem not performed (n = 105)

HF-related death

Deaths = 92 (49.5%)

Deaths = 44 (41.9%)

Dilated cardiomyopathy (n = 35)

Dilated cardiomyopathy (n = 17)

Multi-organ congestion on post-mortem (n = 14)

Valvular heart disease (n = 7)

Valvular heart disease (n = 12)

Hypertensive cardiomyopathy (n = 5)

Myo-pericardial disease (n = 11)

Myo-pericardial disease (n = 4)

Cardiac dystrophy due to brown atrophy (n = 9)

Hypertrophic cardiomyopathy (n = 2)

Restrictive cardiomyopathy (n = 2)

Endocrine-related cardiomyopathy (n = 2)

Hypertensive cardiomyopathy (n = 4)

Cardiomyopathy with an underlying systemic autoimmune condition (n = 2)

Hypertrophic cardiomyopathy (n = 3)

Cardiomyopathy related to cancer treatment (n = 2)

Cardiomyopathy with an underlying systemic autoimmune condition (n = 1)

Cardiomyopathy related to neuromuscular conditions (n = 1)

Cardiomyopathy related to neuromuscular conditions (n = 1)

Restrictive cardiomyopathy (n = 1)

 

Tako-Tsubo cardiomyopathy (n = 1)

Vascular death

Deaths = 41 (22.0%)

Deaths = 34 (32.4%)

Myocardial infarction (n = 13)

Stroke (n = 16)

Non-coronary/non-cerebral atherosclerosis (n = 11)

Non-coronary/non-cerebral atherosclerosis (n = 7)

Stroke (n = 11)

Pulmonary embolism (n = 6)

Pulmonary embolism (n = 4)

Myocardial infarction (n = 5)

Aortic dissection (n = 2)

 

Non-CV death

Deaths = 53 (28.5%)

Deaths = 27 (25.7%)

Malignancies (n = 19)

Kidney failure (n = 10)

Haemorrhage (n = 6)

Decompensated diabetes (n = 9)

Pneumonia (n = 5)

Malignancies (n = 7)

Kidney failure (n = 5)

Pneumonia (n = 1)

Decompensated diabetes (n = 5)

 

Hypovolemic shock (n = 4)a

 

Endocarditis (n = 3)

 

Bronchopneumonia (n = 3)

 

COPD (n = 2)

 

Sepsis (n = 1)

 
  1. Percentages are the proportion of that mode of death in the post-mortem/non-post-mortem group (see Additional file 1: Online Methods for further details of the post-mortem process)
  2. COPD chronic obstructive pulmonary disease, CV cardiovascular, HF heart failure
  3. aThe main cause of the hypovolemic shock was bleeding from ruptured oesophageal varices (three patients) and duodenal peptic ulceration (one patient)