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Table 3 Results of the Cox proportional hazards models

From: Characterization of data-driven clusters in diabetes-free adults and their utility for risk stratification of type 2 diabetes

 

SDPP

MSC

 

Person-time

Cases

Rate per 1000

(95% CI)

Unadjusted

HR (95% CI)

Adjusted

HR (95% CI)

Person-time

Cases

Rate per 1000

(95% CI)

Unadjusted

HR (95% CI)

Adjusted

HR (95% CI)

VLR

44654.0

82

1.84 (1.48, 2.28)

0.41*** (0.32, 0.54)

0.38*** (0.28, 0.50)

1399.40

9

6.43 (3.35, 12.36)

0.55*** (0.51, 0.60)

0.58*** (0.51, 0.66)

LRLB

39519.7

141

3.57 (3.02, 4.21)

0.75* (0.59, 0.95)

0.71** (0.55, 0.90)

1542.28

23

14.91 (9.91, 22.44)

1.23 (0.51, 2.97)

1.24 (0.50, 3.12)

LRHB

31220.8

144

4.61 (3.91, 5.43)

Ref (1.00)

Ref (1.00)

891.15

10

11.22 (6.04, 20.86)

Ref (1.00)

Ref (1.00)

HRHBP

16167.2

191

11.81 (10.25, 13.61)

2.50*** (2.01, 3.11)

2.34*** (1.85, 2.96)

620.84

28

45.10 (31.14, 65.32)

3.39** (1.55, 7.41)

3.26** (1.49, 7.15)

HRBF

26333.1

418

15.87 (14.42, 17.47)

3.58*** (2.96, 4.33)

3.22*** (2.62, 3.96)

885.16

42

47.45 (35.07, 64.21)

3.96*** (2.04, 7.68)

4.00*** (2.05, 7.82)

HRIR

11136.3

250

22.45 (19.83, 25.41)

5.31*** (4.32, 6.52)

5.39*** (4.30, 6.75)

343.10

19

55.38 (35.32, 86.82)

4.74** (1.70, 13.22)

4.52*** (1.66, 12.32)

Total

169031.1

1226

7.25 (6.86, 7.67)

  

5681.93

131

23.06 (19.43, 27.37)

  
  1. SDPP Stockholm Diabetes Prevention Program, MSC Metabolic Syndrome Cohort, HR hazard ratio, 95% CI 95% confidence interval, VLR very low-risk, LRLB low-risk low β-cell function, LRHB low-risk high β-cell function, HRHBP high-risk high blood pressure, HRBF high-risk with predominance of β-cell failure, HRIR high-risk insulin resistance, *p < 0.05, **p < 0.01, ***p < 0.001. Model 1: unadjusted. Model 2: adjusted for self-reported general health (in SDPP), comorbidity, self-reported physical activity level, smoking status, and history of gestational diabetes among women