|  | Estimate | Std. error | z value | Pr( >|z|) |
---|---|---|---|---|---|
Clinical variables | Intercept |  − 0.43249 | 0.18301 |  − 2.363 | 0.0181* |
Sex |  − 0.08264 | 0.16283 |  − 0.508 | 0.6118 | |
Age baseline | 0.09660 | 0.16102 | 0.600 | 0.5486 | |
HDL Imputed | 0.10651 | 0.16663 | 0.639 | 0.5227 | |
TG Imputed |  − 0.27225 | 0.17275 |  − 1.576 | 0.1150 | |
BMI baseline | 0.44999 | 131.228 | 0.343 | 0.7317 | |
Intensity statin therapy |  − 0.11911 | 0.15505 |  − 0.768 | 0.4424 | |
Metabolites | Intercept |  − 0.459189 | 0.704513 |  − 0.652 | 0.5145 |
Sphingosine (d18:2) |  − 0.107924 | 0.260230 |  − 0.415 | 0.6783 | |
Docosenamide | 0.004636 | 0.004572 | 1.014 | 0.3106 | |
Oxo-tricosanoic acid |  − 0.002283 | 0.003195 |  − 0.714 | 0.4750 | |
Tetracosahexaenoic acid |  − 0.003083 | 0.003112 |  − 0.991 | 0.3219 | |
Ketodeoxycholic acid |  − 0.293914 | 0.290994 |  − 1.010 | 0.3125 | |
Stearoylcarnitine |  − 0.436030 | 0.230849 |  − 1.889 | 0.0589 | |
Diglyceride (33:4) | 0.194136 | 0.198864 | 0.976 | 0.3290 | |
Creatine |  − 0.001211 | 0.003222 |  − 0.376 | 0.7071 | |
Tridecanoic acid |  − 0.001950 | 0.003332 |  − 0.585 | 0.5584 | |
Monoacylglycerol (22:6) | 0.003391 | 0.003096 | 1.095 | 0.2733 | |
Dihydroxycholesterol |  − 0.327887 | 0.177616 |  − 1.846 | 0.0649 | |
Biliverdin |  − 0.362871 | 0.179566 |  − 2.021 | 0.0433* | |
Clinical variables and metabolites | Intercept |  − 0.330027 | 0.726670 |  − 0.454 | 0.6497 |
Sphingosine (d18:2) |  − 0.042235 | 0.271197 |  − 0.156 | 0.8762 | |
Docosenamide | 0.004359 | 0.004724 | 0.923 | 0.3561 | |
Oxo-tricosanoic acid |  − 0.002246 | 0.003257 |  − 0.689 | 0.4905 | |
Tetracosahexaenoic acid |  − 0.004089 | 0.003290 |  − 1.243 | 0.2139 | |
Ketodeoxycholic acid |  − 0.321368 | 0.302763 |  − 1.061 | 0.2885 | |
Stearoylcarnitine |  − 0.461926 | 0.236503 |  − 1.953 | 0.0508 | |
Diglyceride (33:4) | 0.184457 | 0.208359 | 0.885 | 0.3760 | |
Creatine |  − 0.001613 | 0.003291 |  − 0.490 | 0.6241 | |
Tridecanoic acid |  − 0.001681 | 0.003458 |  − 0.486 | 0.6268 | |
Monoacylglycerol (22:6) | 0.003439 | 0.003158 | 1.089 | 0.2761 | |
Dihydroxycholesterol |  − 0.307896 | 0.182783 |  − 1.684 | 0.0921 | |
Biliverdin |  − 0.348474 | 0.181466 |  − 1.920 | 0.0548 | |
Sex |  − 0.091159 | 0.178688 |  − 0.510 | 0.6099 | |
Age baseline | 0.142588 | 0.177915 | 0.801 | 0.4229 | |
HDL Imputed | 0.053527 | 0.188053 | 0.285 | 0.7759 | |
TG Imputed |  − 0.223763 | 0.185640 |  − 1.205 | 0.2281 | |
BMI baseline | 0.402986 | 1.322.298 | 0.305 | 0.7605 | |
Intensity Statin Therapy |  − 0.214802 | 0.174998 |  − 1.227 | 0.2197 |