From: Heterogeneity in pragmatic randomised trials: sources and management
Patients: Adults receiving invasive mechanical ventilation and vasoactive drugs for shock Centres: French intensive care units Intervention: Enteral nutrition Control: Parenteral nutrition Outcome: Day 28 all-cause mortality Design: Two parallel-groups, individually randomised trial | |
Centre selection | Both community and university care hospitals were recruited: “44 French ICUs, including 28 (64%) in university hospitals” |
Randomisation | “Randomisation was stratified by centre using permutation blocks of variable sizes” |