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Table 9 ACUDep: acupuncture and counselling for depression

From: Heterogeneity in pragmatic randomised trials: sources and management

Patients: Adults with depression

Centres: General medical practices

Interventions: Acupuncture and counselling

Control: Usual care

Outcome: Depression prevalence assessed with the Patient Health Questionnaire 9 at 3 months

Design: Three parallel-group individually randomised trial

Statistical analysis

“Multiple imputation by chained regression was used for missing data using treatment group, baseline measures (PHQ-9, BDI-II, SF-36, EQ-5D Anxiety/Depression), and demographics (age and gender). The primary analysis was based on the imputed rather than raw data in order to take account of the profile of non-responders.”