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Table 3 Summary of median leukocyte subset percentages identified in colostrum and peripheral blood of lean and obese cohorts

From: A cross-sectional study evidences regulations of leukocytes in the colostrum of mothers with obesity

 

Lean

Obese

Comparisons

Colostrum

Blood

Colostrum

Blood

 Lean

Obese

Colostrum

Blood

Total leukocytes

60.30 (43.00-80.00)

96.50 (91.80-98.50)

62 (41.00-87.90)

97.15 (93.70-98.28)

p=0.54, p=0.80

p <0.0001, p <0.0001

Neutrophils

66.40 (56.95-74.10)

78.2 (70.25-80.05)

70 (61.4-79.5)

73.15 (68.25-78.15)

p=0.35, p=0.48

p=0.007, p=0.51

Eosinophils

0.35 (0.23-0.60)

0.007 (0.004-0.04)

0.34 (0.14-0.67)

0.02 (0.003-0.06)

p=0.84, p=0.23

p<0.0001, p<0.0001

Basophils

0.65 (0.22-0.77)

0.3 (0.21-0.36)

0.5 (0.23-0.97)

0.29 (0.20-0.47)

p=0.93, p=0.46

p=0.049, p=0.2

Immature granulocytes

0.81 (0.65-1.26)

0.58 (0.15-1.06)

0.73 (0.42-2.53)

0.30 (0.12-1.04)

p=0.90, p=0.97

p=0.09, p=0.036

Myeloid progenitors

0.28 (0.11-0.55)

0.22 (0.08-0.91)

0.23 (0.11-0.62)

0.14 (0.08-0.32)

p=0.84, p=0.17

p=0.83, p=0.28

CD16+ monocytes

0.07 (0.03-0.16)

0.19 (0.1-0.28)

0.04 (0.02-0.1)

0.15 (0.05-0.31)

p=0.49, p=0.95

p=0.0063, p=0.13

CD16- monocytes

1.24 (0.62-4.80)

3.23(1.4-4.4)

2.03 (0.57-3.42)

2.2 (0.8-3.4)

p=0.78, p=0.45

p=0.43, p=0.83

B lymphocytes

0.41 (0.17-0.70)

2.13 (1.67-2.75)

0.17 (0.06-0.21)

2.63 (2.09-3.43)

p=0.029, p=0.09

p<0.0001, p<0.0001

Non-cytotoxic T cells

6.95 (2.09-9.43)

10.9 (8.94-17.50)

3.81 (1.4-7.56)

13.10 (9.40-19.75)

p=0.45, p=0.61

p<0.0001, p<0.0001

NK/Cytotoxic T cells

0.20 (0.11-0.62)

0.73 (0.37-1.17)

0.17 (0.05-0.6)

0.91 (0.41-1.77)

p=0.63, p=0.17

p=0.006, p<0.0001

  1. Frequency of leukocyte subpopulations expressed as median % (interquartile range). Total leukocytes from live singlets are reported and then used as the parent for leukocyte subpopulation frequencies. Non-parametric Mann-Whitney U tests were used to compare leukocyte proportions measured per tissue between cohorts (first p value = colostrum, second p value = blood). Intra-individual comparisons were performed using Wilcoxon matched-pairs signed rank tests, comparing leukocyte proportions between blood and colostrum within each cohort (first p value = lean, second p value = obese. p values < 0.05 were considered significant
  2. Colostrum vs. Blood (p value) within each cohort, analysis btw tissues (Lean, obese)
  3. Obese vs. Lean (p value) (colostrum, blood)