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Table 3 Distribution of characteristics and their associations with prophylactic antibiotic use for vaginal delivery only

From: Prophylactic antibiotic use during labor and delivery in China: a nationwide, multicenter, hospital-based, cross-sectional study

Characteristics

Unweighted

Weighted

Total, no.

Antibiotic use, no.

Proportion, %

Prevalence, %

OR (95%CI, P value)

AOR (95%CI, P value)

Hospital level

 Secondary

10,634

1974

54.0

29.6

1 [reference]

1 [reference]

 Tertiary

34,871

7669

46.0

24.0

0.75 (0.32–1.77, P = 0.507)

0.78 (0.35–1.72, P = 0.533)

Hospital type

 Maternity

22,505

3446

44.5

14.5

1 [reference]

1 [reference]

 General

23,000

6197

55.5

37.0

3.47 (1.65–7.28, P = 0.001)

3.36 (1.58–7.11, P = 0.002)

Mode of delivery

 Spontaneous vaginal

44,220

9080

97.5

26.2

1 [reference]

1 [reference]

 Operative vaginal

1285

563

2.5

57.8

3.85 (1.22–12.13, P = 0.022)

3.36 (1.27–8.86, P = 0.015)

Premature rupture of membrane

 No

38,110

6323

85.8

23.8

1 [reference]

1 [reference]

 Yes

7351

3303

14.2

46.2

2.74 (1.82–4.14, P < 0.001)

2.86 (1.79–4.55, P < 0.001)

Preterm labor

 No

41,672

8212

93.6

25.6

1 [reference]

1 [reference]

 Yes

3232

1258

6.4

43.8

2.27 (1.75–2.94, P < 0.001)

2.27 (1.80–2.87, P < 0.001)

Meconium-stained amniotic fluid

 No

41,441

8423

89.6

25.6

1 [reference]

1 [reference]

 Yes

3931

1171

10.4

39.3

1.88 (1.33–2.68, P = 0.001)

1.82 (1.16–2.85, P = 0.010)

Episiotomy

 No

33,187

5879

65.3

22.4

1 [reference]

1 [reference]

 Yes

12,068

3734

34.7

35.8

1.93 (1.53–2.42, P < 0.001)

1.48 (1.02–2.16, P = 0.039)

Perineal laceration degree

 None, I and II

44,945

9540

99.8

27.0

1 [reference]

1 [reference]

 III and IV

72

25

0.2

35.0

1.45 (0.36–5.94, P = 0.600)

1.78 (0.58–5.46, P = 0.308)

  1. OR odds ratio, AOR adjusted odds ratio (adjusted for all variables mentioned above), CI confidence interval