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Table 1 Clinical characteristics of AD patients in the China RSF multi-center cohort

From: Speech silence character as a diagnostic biomarker of early cognitive decline and its functional mechanism: a multicenter cross-sectional cohort study

Multi-center in China

NC (n = 113)

MCI (n = 95)

AD (n = 116)

Statistics

P value

Gender, female, n, %

71 (62.8%)

54 (56.8%)

61 (52.6%)

2.617

0.270

Age (years)

67.6 ± 7.9

73.0 ± 6.8

76.4 ± 8.2

39.104

0.000

Education (years)

12.2 ± 2.9

11.5 ± 3.1

11.3 ± 3.5

5.293

0.071

ApoE e4 typea, n, %

11/54, 20.4%

20/57, 35.1%

39/68, 57.4%

17.754

0.000

MMSE

28.7 ± 1.2

26.2 ± 2.3

19.0 ± 4.2

234.738

0.000

MoCA-B

26.0 ± 2.5

20.7 ± 3.6

14.5 ± 4.7

212.456

0.000

ACE

86.2 ± 7.4

73.8 ± 9.3

54.1 ± 13.6

200.906

0.000

 ACE-fluence

9.3 ± 2.0

7.6 ± 2.0

5.2 ± 2.2

125.069

0.000

 ACE-language

23.7 ± 2.5

20.3 ± 3.6

16.6 ± 5.2

120.305

0.000

PSD

33.5 ± 10.5

44.1 ± 12.8

51.2 ± 14.3

86.866

0.000

  1. aData on ApoE e4 type was available in 54, 57, and 68 of NC, aMCI, and AD patients, respectively. For acronyms, please refer to the “Methods” section