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Fig. 1 | BMC Medicine

Fig. 1

From: Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk

Fig. 1

Data overview, quality control, and phenotype selection. Panel A shows the main phenotypes investigated in the observational analyses, where exposure variables and the outcome (EC) were derived from UKBB data. Panel B shows the main phenotypes investigated in the univariate and multivariable MR analyses. * indicates that we were unable to perform MR analyses on the years taking oral contraceptive pill phenotype as no genome-wide significant variants were identified in the GWAS. EC, endometrial cancer; ECAC, Endometrial Cancer Association Consortium; E2C2, Epidemiology of Endometrial Cancer Consortium; GWAS, genome-wide association study; MR, Mendelian randomization; UKBB, UK Biobank

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BMC Medicine

ISSN: 1741-7015

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