Table 1 Baseline characteristics of the participants with and without CVD
Characteristics | No. (%) | Noncases (n = 90,197) | |||
|---|---|---|---|---|---|
Incidence CVD | |||||
At age < 55 y (n = 1241) | At 55 to < 65 y (n = 2693) | At 65 to < 75 y (n = 2273) | At age ≥ 75 y (n = 1380) | ||
Clinical risk factors | |||||
 Age, y | 44.29 ± 5.56 | 53.37 ± 4.20 | 62.50 ± 4.95 | 72.66 ± 5.51 | 50.96 ± 12.59 |
 Men, n (%) | 1097 (88.40) | 2399 (89.08) | 2028 (89.22) | 1246 (90.29) | 71,048 (78.77) |
 High school or above, n (%) | 55 (4.49) | 66 (2.54) | 56 (2.62) | 36 (3.06) | 6389 (7.371) |
 Income > 800 yuan/month, n (%) | 143 (11.69) | 296 (11.44) | 254 (11.92) | 191 (16.26) | 12,427 (14.34) |
 Current smoker, n (%) | 570 (46.68) | 1112 (42.92) | 767 (35.62) | 302 (24.34) | 29,577 (33.85) |
 Current drinker, n (%) | 546 (44.64) | 1000 (38.60) | 730 (33.97) | 354 (28.55) | 32,760 (37.48) |
 Physical inactivity, n (%) | 133 (10.88) | 229 (8.88) | 111 (5.23) | 53 (4.51) | 7631 (8.82) |
 Hypertension, n (%) | 720 (58.02) | 1734 (64.39) | 1556 (68.46) | 946 (68.55) | 36,969 (40.99) |
 Diabetes, n (%) | 175 (14.10) | 486 (18.05) | 434 (19.09) | 209 (15.14) | 7438 (8.25) |
 Dyslipidemia, n (%) | 557 (44.88) | 1183 (43.93) | 980 (43.11) | 513 (37.17) | 31,145 (34.53) |
 Metabolism syndrome, n (%) | 249 (20.06) | 642 (23.84) | 583 (25.65) | 316 (22.90) | 11,967 (13.27) |
 Body mass index, kg/m.2 | 26.18 ± 3.61 | 25.91 ± 3.46 | 25.54 ± 3.37 | 25.12 ± 3.42 | 24.96 ± 3.49 |
 Overweight or obese, n (%) | 748 (60.27) | 1562 (58.00) | 1224 (53.85) | 675 (48.91) | 42,098 (46.67) |
 Systolic blood pressure, mm Hg | 138.26 ± 23.68 | 141.36 ± 22.75 | 144.56 ± 22.96 | 144.45 ± 21.27 | 129.64 ± 20.41 |
 Diastolic blood pressure, mm Hg | 90.05 ± 14.57 | 89.71 ± 13.18 | 88.00 ± 11.95 | 84.04 ± 10.73 | 82.96 ± 11.58 |
Lipids profile | |||||
 Total cholesterol, mmol/L | 5.21 ± 1.15 | 5.12 ± 1.18 | 5.11 ± 1.22 | 5.02 ± 1.20 | 4.93 ± 1.14 |
 Triglycerides, mmol/L | 2.05 ± 1.62 | 1.97 ± 1.58 | 1.81 ± 1.45 | 1.63 ± 1.21 | 1.66 ± 1.36 |
 LDL cholesterol, mmol/L | 2.44 ± 0.93 | 2.40 ± 0.94 | 2.39 ± 1.14 | 2.33 ± 1.08 | 2.34 ± 0.90 |
 HDL cholesterol, mmol/L | 1.54 ± 0.40 | 1.55 ± 0.41 | 1.57 ± 0.44 | 1.59 ± 0.49 | 1.55 ± 0.40 |
 Total/HDL cholesterol | 3.58 ± 1.37 | 3.48 ± 1.12 | 3.48 ± 1.55 | 3.39 ± 1.47 | 3.39 ± 3.26 |
 Triglyceride/HDL cholesterol | 1.44 ± 1.37 | 1.36 ± 1.18 | 1.28 ± 1.48 | 1.13 ± 1.17 | 1.17 ± 2.26 |
 Non-HDL-C, mmol/L | 3.67 ± 1.10 | 3.56 ± 1.17 | 3.53 ± 1.21 | 3.42 ± 1.21 | 3.38 ± 1.11 |
 Remnant cholesterol, mmol/L | 1.23 ± 1.15 | 1.16 ± 1.25 | 1.14 ± 1.32 | 1.10 ± 1.36 | 1.04 ± 1.15 |
Metabolic and Inflammatory | |||||
 Fasting blood glucose, mmol/L | 5.86 ± 2.17 | 6.04 ± 2.29 | 5.92 ± 2.18 | 5.69 ± 1.99 | 5.43 ± 1.61 |
 Triglyceride-glucose index | 8.90 ± 0.75 | 8.90 ± 0.73 | 8.81 ± 0.71 | 8.69 ± 0.68 | 8.64 ± 0.69 |
 eGFR, ml/min/1.73/m.2 | 86.25 ± 21.83 | 80.9 ± 23.98 | 76.6 ± 27.72 | 71.43 ± 40.79 | 82.56 ± 25.47 |
 Creatinine, μmol/L | 94.50 ± 41.98 | 94.74 ± 40.29 | 93.55 ± 33.05 | 95.49 ± 35.58 | 91.56 ± 29.85 |
 Serum uric acid, μmol/L | 301.01 ± 88.77 | 295.31 ± 84.63 | 306.58 ± 89.47 | 314.79 ± 94.12 | 287.85 ± 83.18 |
 Hs-CRP, mg/L | 2.49 ± 5.32 | 2.66 ± 4.60 | 3.29 ± 7.05 | 3.94 ± 8.60 | 2.33 ± 6.48 |
 White blood cell count, *109/L | 7.20 ± 1.98 | 7.04 ± 2.77 | 7.10 ± 13.09 | 6.50 ± 2.13 | 6.83 ± 9.86 |
 Neutrophil count, *109/L | 4.34 ± 1.50 | 4.18 ± 1.71 | 4.13 ± 2.36 | 3.91 ± 1.29 | 3.97 ± 2.91 |
 Platelet, *109/L | 219.23 ± 82.37 | 205.74 ± 56.82 | 198.56 ± 79.37 | 189.93 ± 78.41 | 211.22 ± 746.16 |
 Red blood cell count, *109/L | 4.96 ± 0.50 | 4.89 ± 0.48 | 5.37 ± 16.04 | 4.67 ± 0.48 | 5.05 ± 26.46 |