|  | Males | Females | ||||
---|---|---|---|---|---|---|---|
LS7 tertile | Total | 3rd tertile | 2nd tertile | 1st tertile | 3rd tertile | 2nd tertile | 1st tertile |
(LS7 Score) | (0–14) | 10–14 | 8–9 | 0–7 | 10–14 | 8–9 | 0–7 |
Sample size, N | 35,207 | 3,827 | 5,549 | 7,736 | 4,860 | 5,577 | 7,658 |
Age (mean ± SD) | 46.6 ± 16.7 | 38.2 ± 14.9 | 45.2 ± 15.9 | 51.5 ± 15.5 | 38.4 ± 14.0 | 46.8 ± 16.7 | 54.9 ± 15.9 |
Female, N(%) | 18,095 (51.4%) | - | - | - | - | - | - |
CVD, N(%) | 3391 (7.57%) | 156 (3.26%) | 483 (6.54%) | 1337 (13.88%) | 90 (1.81%) | 313 (4.88%) | 1012 (11.73%) |
Race, N(%) | |||||||
 White | 16,960 (70.8%) | 1,853 (69.8%) | 2,760 (71.7%) | 3,756 (71.6%) | 2,304 (69.9%) | 2,620 (69.6%) | 3,667 (71.8%) |
 Black | 6,846 (10.3%) | 696 (9.1%) | 1,057 (9.4%) | 1,555 (9.8%) | 724 (8.2%) | 1,067 (11.2%) | 1,747 (13.2%) |
 Hispanic | 9,101 (13.2%) | 904 (14.0%) | 1,377 (13.7%) | 2,037 (13.7%) | 1,329 (13.9%) | 1,516 (13.5%) | 1,938 (11.2%) |
 Other | 2,300 (5.6%) | 374 (7.1%) | 355 (5.2%) | 388 (4.8%) | 503 (7.9%) | 374 (5.7%) | 306 (3.9%) |
Education, N(%) | |||||||
 < 9th grade | 4,246 (5.9%) | 275 (3.9%) | 637 (5.7%) | 1,268 (8.1%) | 330 (3.5%) | 615 (5.5%) | 1,121 (7.5%) |
 9–11th grade | 5,503 (12.1%) | 466 (8.5%) | 847 (11.7%) | 1,392 (14.9%) | 479 (6.9%) | 815 (11.3%) | 1,504 (16.7%) |
 High school | 8,182 (24.0%) | 803 (20.2%) | 1,328 (24.8%) | 1,937 (27.2%) | 846 (16.3%) | 1,329 (24.6%) | 1,939 (28.2%) |
 Some college | 9,829 (30.8%) | 1,084 (29.2%) | 1,450 (28.6%) | 1,883 (29.1%) | 1,538 (32.7%) | 1,695 (33.5%) | 2,179 (31.8%) |
 College graduate | 7,447 (27.2%) | 1,199 (38.2%) | 1,287 (29.3%) | 1,256 (20.8%) | 1,667 (40.6%) | 1,123 (25.0%) | 915 (15.8%) |
Mortality rate, N(%) | |||||||
 All-cause | 4,228 (8.5%) | 259 (4.2%) | 658 (7.2%) | 1,491 (14.3%) | 162 (2.2%) | 475 (7.0%) | 1,183 (12.7%) |
 CVD related | 1,311 (2.4%) | 57 (0.9%) | 201 (2.0%) | 499 (4.5%) | 40 (0.5%) | 118 (1.6%) | 396 (3.8%) |
 Non-CVD related | 2,917 (6.1%) | 202 (3.3%) | 457 (5.2%) | 992 (9.8%) | 122 (1.7%) | 357 (5.4%) | 787 (8.9%) |
Number of prescription medications, N(%) | |||||||
 8+ | 27,662 (80.82%) | 3,605 (94.66%) | 4,753 (88.28%) | 5,369 (72.87%) | 4,539 (92.66%) | 4,630 (82.44%) | 4,766 (62.69%) |
 4-7 | 5,711 (14.79%) | 195 (4.57%) | 663 (10.14%) | 1714 (20.06%) | 278 (6.57%) | 786 (14.79%) | 2,075 (26.66%) |
 0-3 | 1,813 (4.39%) | 26 (0.77%) | 129 (1.58%) | 649 (7.06%) | 40 (0.77%) | 159 (2.77%) | 810 (10.66%) |
33-Item Frailty Index, N(%) | |||||||
 < 0.1 | 22,538 (70.4%) | 3,296 (89.2%) | 4,089 (79.8%) | 4,339 (64.3%) | 3,978 (84.4%) | 3,575 (67.3%) | 3,261 (47.9%) |
 0.1–0.2 | 7,084 (17.5%) | 387 (8.2%) | 871 (13.2%) | 1,711 (19.4%) | 695 (12.1%) | 1,316 (22.4%) | 2,104 (25.7%) |
 0.2–0.3 | 2,983 (6.8%) | 91 (1.7%) | 359 (4.4%) | 892 (8.8%) | 128 (2.6%) | 410 (6.4%) | 1,103 (13.5%) |
 > 0.3 | 2,602 (5.3%) | 53 (0.9%) | 230 (2.5%) | 794 (7.5%) | 59 (0.8%) | 276 (4.0%) | 1,190 (12.9%) |
 Mean ± SD | 0.09 ± 0.10 | 0.05 ± 0.06 | 0.07 ± 0.08 | 0.11 ± 0.11 | 0.06 ± 0.06 | 0.09 ± 0.09 | 0.15 ± 0.12 |