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Fig. 3 | BMC Medicine

Fig. 3

From: Exercise training attenuates pulmonary inflammation and mitochondrial dysfunction in a mouse model of high-fat high-carbohydrate-induced NAFLD

Fig. 3

Treadmill running ameliorated the development of pulmonary inflammation and fibrogenic pattern in HFHC-induced mice. A Pulmonary H&E staining (upper panel) and Masson’s trichrome staining (lower panel) (n = 4 per group). B Percentage of fibrotic area (n = 4 per group). C Representative mRNA levels of genes involved in inflammation (TNF-α, IL-1β) in lung tissue (n = 3–5 per group). D Representative mRNA levels of genes involved in fibrosis (Col1a1, Timp1) (n = 3–5 per group). Gene expression were quantified in triplicate using real-time PCR and normalized to β-actin. Data are presented as mean ± S.D. Statistical analyses were performed by two-way ANOVA. Post hoc t-tests were performed to compare the differences between the 2 groups, if needed

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BMC Medicine

ISSN: 1741-7015

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