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Table 1 Demographic and clinical characteristics among proguanil/atovaquone users and matched comparisons

From: Proguanil and atovaquone use is associated with lower colorectal cancer risk: a nationwide cohort study

 

Proguanil/atovaquone users (N=16,817)

Non-users (N=168,170)

 

No.

%

No.

%

Age at index

 ≤50

6642

39.5

66,420

39.5

 51–60

4924

29.3

49,240

29.3

 >60

5251

31.2

52,510

31.2

Sex

 Males

8196

48.7

81,960

48.7

 Females

8621

51.3

86,210

51.3

Birth country

 Sweden

16,449

97.8

163,114

97.0

 Northern European country

122

0.7

2045

1.2

 Western European country

50

0.3

489

0.3

 Eastern European country

68

0.4

1064

0.6

 African country

20

0.1

63

0.1

 Middle-Eastern country

50

0.3

784

0.5

 Others

58

0.4

611

0.3

Highest education level, year

 1–9

1060

6.3

29,582

17.6

 10–11

4808

28.6

78,241

46.5

 ≥12

10,949

65.1

60,347

35.9

Income

 Lowest

2839

16.9

44,167

26.3

 Middle-low

3521

20.9

47,135

28.0

 Middle-high

3551

21.1

38,168

22.7

 Highest

6906

41.1

38,700

23.0

IBD

 No

16,662

99.1

166,063

98.8

 Yes

155

0.9

2107

1.2

Obesity

 No

16,681

99.2

165,429

98.4

 Yes

136

0.8

2741

1.6

COPD

 No

15,956

94.9

158,059

94.0

 Yes

861

5.1

10,111

6.0

Colonoscopy

 No

16,199

96.3

162,277

96.5

 Yes

618

3.7

5893

3.5

CCI

 0

14,686

87.3

140,683

83.7

 1

1699

10.1

19,707

11.7

 2

320

1.9

5053

3.0

 ≥3

112

0.7

2727

1.6

Outpatient visits, per year

 0

9884

58.8

85,803

51.0

 1

4959

29.5

48,408

28.8

 2

1170

6.9

16,447

9.8

 ≥3

804

4.8

17,512

10.4

Prescription of other medicines

 Aspirin

1089

6.5

13,243

7.9

 Statin

1826

10.9

21,105

12.6

  1. IBD inflammatory bowel disease, COPD chronic obstructive pulmonary disease, CCI Charlson Comorbidity Index score