Table 3 The comparison of the NMSS domain at baseline and 1- and 2-year follow-ups

D1: Cardiovascular

2

4

2

5

3

7

<0.001^a

a,b

D2: Sleep/fatigue

5

8

6

7

6

9

0.004^a

b

D3: Mood/apathy

4

16

6

14

6

20

0.024^a

b

D4: Perceptual problems/hallucinations

0

0

0

0

0

0

<0.001^a

a,b

D5: Attention/memory

2

5

3

5

4

6

<0.001^a

a,b,c

D6: Gastrointestinal

2.5

6

4

7

5

8

<0.001^a

a,b,c

D7: Urinary

9

18

9.5

16

17

18

<0.001^a

b,c

D8: Sexual function

0

8

2

8

8

14

<0.001^a

a,b,c

D9: Miscellaneous

2

8

4

7

3

6

0.053

NMSS total score

41

45

46

47

65

50

<0.001^a

a,b,c