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Table 2 Frequency of Kenyan parasites harboring Pfpm2/3 and Pfmdr1 multiple copies between 2008 and 2021

From: Impact of parasite genomic dynamics on the sensitivity of Plasmodium falciparum isolates to piperaquine and other antimalarial drugs

Study period

 
  

2008–2013

2014–2017

2018–2021

P-value

Genotype

 

N

Proportion

N

Proportion

N

Proportion

 

Pfmdr1

Single copy

57

98.3%

122

96.1%

92

96.8%

 

Multi-copy

1

1.7%

5

3.9%

3

3.2%

0.7304

Pfpm2

Single copy

65

97.0%

118

98.3%

97

98.0%

 

Mult-copy

2

3.0%

2

1.7%

2

2.0%

0.4522

Pfpm3

Single copy

80

89.9%

100

93.5%

96

96.0%

 

Multi-copy

9

10.1%

7

6.5%

4

4.0%

0.8318

  1. Pfmdr1 Plasmodium falciparum multi-drug resistance 1 gene, Pfpm2 Plasmodium falciparum plasmepsin 2, Pfpm3 Plasmodium falciparum plasmepsin 3, N number of samples
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BMC Medicine

ISSN: 1741-7015

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