From: Association of shift work with incident dementia: a community-based cohort study
Characteristics | Current work schedule | |
---|---|---|
Non-shift workers | Shift workers | |
Sample size, n | 143,272 | 27,450 |
Age (year) | 52.8 ± 7.1 | 51.8 ± 7.0 |
Sex/female | 74,896 (52.3) | 12,010 (43.8) |
Ethnicity/White | 136,909 (95.6) | 24,963 (90.9) |
Education | ||
Higher | 81,636 (57.0) | 12,200 (44.4) |
Upper secondary | 12,506 (8.7) | 2064 (7.5) |
Lower secondary | 23,551 (16.4) | 5039 (18.4) |
Vocational | 9158 (6.4) | 3163 (11.5) |
Other | 16,421 (11.5) | 4984 (18.2) |
Townsend deprivation index category | ||
Low | 38,512 (26.9) | 5318 (19.4) |
Intermediate | 73,149 (51.1) | 13,143 (47.9) |
High | 31,611 (22.1) | 8989 (32.7) |
DM | 4719 (3.3) | 1227 (4.5) |
HTN | 29,561 (20.6) | 6151 (22.4) |
Stroke | 1150 (0.8) | 233 (0.8) |
CHD | 3205 (2.2) | 775 (2.8) |
Cholesterol-lowering medication | 15,025 (10.5) | 3222 (11.7) |
Antihypertensives | 19,491 (13.6) | 4140 (15.1) |
Aspirin | 13,648 (9.5) | 2826 (10.3) |
BMI (kg/m2) | 27.05 ± 4.59 | 27.96 ± 4.84 |
SBP (mmHg) | 134.69 ± 17.75 | 135.23 ± 17.48 |
TC (mmol/L) | 5.69 ± 1.08 | 5.65 ± 1.08 |
TG (mmol/L) | 1.68 ± 1.02 | 1.80 ± 1.11 |
HDL (mmol/L) | 1.45 ± 0.37 | 1.38 ± 0.36 |
LDL (mmol/L) | 3.56 ± 0.83 | 3.56 ± 0.83 |
HbA1c (%) | 5.36 ± 0.54 | 5.43 ± 0.62 |
No current smoking | 129,339 (90.3) | 23,275 (84.8) |
Alcohol consumption at least weekly | 106,793 (74.5) | 18,306 (66.7) |
Healthy diet | 91,682 (64.0) | 16,019 (58.4) |
Regular physical activity | 72,331 (50.5) | 16,702 (60.8) |
Genetic predisposition to dementia by PRS category | ||
Low | 71,309 (49.8) | 13,546 (49.3) |
Intermediate | 36,223 (25.3) | 7226 (26.3) |
High | 35,740 (24.9) | 6678 (24.3) |
Years of work (years) | 12.85 ± 10.65 | 13.15 ± 10.66 |
Sleep duration category (h/day) | ||
≤ 6 | 34,289 (23.9) | 8690 (31.7) |
7–8 | 102,900 (71.8) | 17,337 (63.2) |
≥ 9 | 6083 (4.2) | 1423 (5.2) |
Chronotype | ||
Definitely a “morning” person | 37,047 (25.9) | 7245 (26.4) |
More a “morning” than “evening” person | 52,168 (36.4) | 8763 (31.9) |
More an “evening” than a “morning” person | 41,123 (28.7) | 8337 (30.4) |
Definitely an “evening” person | 12,934 (9.0) | 3105 (11.3) |