Association of shift work with incident dementia: a community-based cohort study

Table 4 Hazard ratios for secondary outcome associated with current work schedule

Secondary outcomes	Groups	Sample size	Cases	Person-years	Incidence rate per 100,000 person-years	Model 1	Model 2
AD	Non-shift workers	143,272	223	1,754,038	12.71	Ref	Ref
	Shift workers	27,450	48	335,241	14.31	1.37 [1.00, 1.87]	1.23 [0.90, 1.69]
	P value	-	-	-	-	0.05	0.20
VD	Non-shift workers	143,272	101	1,754,274	5.75	Ref	Ref
	Shift workers	27,450	26	335,335	7.75	1.63 [1.06, 2.50]	1.46 [0.94, 2.27]
	P value	-	-	-	-	0.02	0.09
Other types of dementia	Non-shift workers	143,272	418	1,753,631	23.83	Ref	Ref
	Shift workers	27,450	99	335,172	29.53	1.44 [1.15, 1.79]	1.34 [1.07, 1.68]
	P value	-	-	-	-	0.001	0.01

Abbreviations: AD Alzheimer’s disease, VD vascular dementia
Data are hazard ratios (95% confidence interval). Model 1 was adjusted for age at baseline and sex. Model 2 was adjusted for terms in model 1, ethnicity, education, and socioeconomic status

ISSN: 1741-7015