Fig. 1
From: Bidirectional genetic overlap between bipolar disorder and intelligence
Polygenic overlap between bipolar disorder (BD) and intelligence (IQ). A The estimated number of causal variants shared (grey) between BD and IQ calculated by MiXeR, and the genetic correlation (rg= −0.066) is estimated by LDSC. B Conditional Q-Q plots of nominal versus empirical −log10 transformed P values in the primary phenotype as a function of significance of SNP associations with the secondary phenotype at the level of P ≤ 1.00 (all SNPs, blue lines), P ≤ 0.1 (red lines), P ≤ 0.01 (yellow lines) and P ≤ 0.001 (purple lines). The dashed line is the expected Q-Q plot under the null hypothesis