Fig. 2

Dose-response curves for frailty phenotype scores and incidence of diabetic microvascular complications. Data are presented as adjusted hazard ratios with the 95% confidence interval shown as shading. The restricted cubic spline models adjusted for age, sex, ethnicity, educational attainment, Townsend deprivation index, annual household income, assessment centers, smoking status, alcohol intake, healthy diet score, BMI, no. of long-term conditions, diabetes duration, HbA1c, diabetes medication use, lipid-lowering treatment, antihypertensive medication use, and aspirin use