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Fig. 4 | BMC Medicine

Fig. 4

From: A novel 450-nm laser-mediated sinoporphyrin sodium-based photodynamic therapy induces autophagic cell death in gastric cancer through regulation of the ROS/PI3K/Akt/mTOR signaling pathway

Fig. 4

Apoptotic effects of 450-nm laser/DVDMS-mediated PDT on GC cells. A, B Heatmap and volcano plot of the DEGs in HGC27 cells between BL-PDT group vs. BL group. C, D GO and KEGG enrichment analysis of the DEGs in HGC27 cells. E, F Flow cytometry analysis of the apoptosis in GC cells after the treatment of 24 h (n = 3, mean ± SD). G Western blotting analysis of the expression levels of apoptosis-related proteins after the treatment of 24 h. H Quantitative analysis of G (n = 3, mean ± SD). *p < 0.05, **p < 0.01, and ***p < 0.001

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BMC Medicine

ISSN: 1741-7015

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