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Fig. 5 | BMC Medicine

Fig. 5

From: A novel 450-nm laser-mediated sinoporphyrin sodium-based photodynamic therapy induces autophagic cell death in gastric cancer through regulation of the ROS/PI3K/Akt/mTOR signaling pathway

Fig. 5

450-nm laser/DVDMS-mediated PDT induced autophagy flux in GC cells. A Representative fluorescence images of autophagy dots in GC cells after the treatment of 24 h. Scale bar = 10 μm. B Quantitative analysis of A (n = 3, mean ± SD). C Typical TEM images of the autophagic vacuoles (indicated by the red arrow) after PDT for 24 h. D Western blotting analysis of the expression levels of autophagy-related proteins after the treatment of 24 h. E Quantitative analysis of D (n = 3, mean ± SD). F Western blotting analysis of the effect of inhibitor CQ for 4 h on autophagy. G Quantitative analysis of F (n = 3, mean ± SD). *p < 0.05, **p < 0.01, and ***p < 0.001

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BMC Medicine

ISSN: 1741-7015

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