Table 2 Univariate and multivariate analysis of prognostic factors for survivals (by Cox regression)

Age (≥ 60y, n = 23 vs. < 60y, n = 33)

0.78

1.12 (0.51–2.47)

0.86

0.93 (0.39–2.17)

Gender (male, n = 36 vs. female, n = 20)

0.82

0.91 (0.41–2.05)

0.12

1.93 (0.84–4.47)

Primary site (oral, n = 9 vs. extra oral, n = 47)

0.67

0.82 (0.33–2.04)

0.25

0.57 (0.22–1.47)

Ann Arbor stage (III/IV, n = 21 versus I/ II, n = 35)

0.27

1.58 (0.70–3.56)

0.03

2.58 (1.10–6.07)

0.66

1.32 (0.37–4.65)

B symptom (yes, n = 22 vs. no, n = 27)

0.36

0.65 (0.26–1.63)

0.38

0.66 (0.26–1.66)

LDH level (elevated, n = 17 versus normal, n = 24)

0.16

0.51 (0.19–1.32)

0.03

0.33 (0.12–0.91)

0.06

0.35 (0.12–1.05)

EBER (positive, n = 10 vs. negative, n =10)

0.37

0.60 (0.19–1.85)

0.21

0.49 (0.16–1.49)

Ki67 (≥ 80%, n = 40 vs. < 80%, n = 16)

0.34

0.63 (0.25–1.61)

0.56

0.75 (0.28–1.98)

Complete response (yes, n = 25 versus. No, n = 31)

0.001

3.51 (1.65–7.50)

0.003

3.89 (1.60–9.45)

0.001

7.03 (2.33–21.17)

0.002

13.24 (2.58–67.99)