Fig. 4

The ENG effectively alleviated hypoxemia and improved pulmonary hemodynamics in the porcine PAH model. A A schematic of the connection of the ENG to the ventilator and the acquisition of hemodynamic data. B Western blotting for sGC and PKG in the lung tissues of piglets with PAH in the presence or absence of NO inhalation (n=6/group). C PaO2 detection in piglets with PAH in the presence or absence of NO inhalation or the sham group at the indicated timepoint (n=6/group). D–F The measurement of PAP (D); SV, CO, and CI (E); and PVR and PVRI (F). * P<0.05, ** P<0.01; compared to the PAH group, as analyzed by Student’s t test (B) or two-way ANOVA with repeated measures (C–F)