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Table 1 Basic characteristics for mothers and offspring at follow-up stratified by children’s LTL tertiles

From: Early emergence of sexual dimorphism in offspring leukocyte telomere length was associated with maternal and children’s glucose metabolism—a longitudinal study

 

Tertile 1 (n=294)

Tertile 2 (n=294)

Tertile 3 (n=294)

Total (n=882)

 

Children’s LTL

0.97 ± 0.28

1.50 ± 0.11

2.00 ± 0.26

1.49 ± 0.48

 

Cord blood LTL

1.42 ± 0.52

1.65 ± 0.52

2.05 ± 0.61

1.74 ± 0.62

<0.001

Maternal

T1

T2

T3

Total

P

 Maternal age EDC (yr)

30.7 ± 4.9

31.4 ± 4.4

31.8 ± 4.5

31.3 ± 4.6

<0.001

 Pre-preg BMI (kg/m2)

20.9 ± 2.8

21.0 ± 3.0

20.8 ± 2.8

20.9 ± 2.9

0.569

 Prenatal smoking #

6 (2.0)

5 (1.7)

2 (0.7)

13 (1.5)

0.363

 Parity, null vs ≥ 1, null#

179 (60.9)

178 (60.5)

159 (54.1)

516 (58.5)

0.346

 Maternal current DM#

25 (8.5)

36 (12.2)

37 (12.6)

98 (11.1)

0.214

 Paternal current DM#

31 (10.5)

32 (10.9)

31 (10.5)

94 (10.7)

0.989

 C-section#

59 (20.1)

79 (26.9)

73 (24.8)

211 (23.9)

0.140

 Breastfeeding#

139 (47.3)

157 (53.4)

142 (48.3)

438 (49.7)

0.312

 Birthweight (g)

3227 ± 358

3238 ± 402

3202 ± 407

3220 ± 392

0.516

 Maternal FBG (mmol/L)

4.3 ± 0.3

4.4 ± 0.3

4.4 ± 0.3

4.4 ± 0.3

0.059

 Maternal OGTT GAUC

12.9 ± 1.9

13.3 ± 2.3

13.3 ± 2.1

13.2 ± 2.2

0.043

Children

T1

T2

T3

Total

p

 Follow-up age (year)

7.0 ± 0.4

7.0 ± 0.4

7.0 ± 0.5

7.0 ± 0.4

0.495

 Sex (female %)#

124 (42.2)

134 (45.6)

163 (55.4)

421 (47.7)

0.004

 BMI (kg/m2)

15.2 ± 2.5

15.2 ± 2.3

14.8 ± 2.0

15.1 ± 2.3

0.027

 Children’s exercise levels (0, 1, 2)

   

0.003

  0

20 (6.8)

31 (10.5)

38 (12.9)

89 (10.1)

 

  1

155 (52.7)

150 (51.0)

162 (55.1)

467 (52.9)

 

  2

119 (40.5)

134 (45.6)

94 (32.0)

347 (39.3)

 
  1. #Shown in number (percentage). *Shown with median [Q1–Q3] PLUS p-values comparison with natural log transformation in correlation test. P shown at the last column compare for the trend between T1, T2 and T3 only