Early emergence of sexual dimorphism in offspring leukocyte telomere length was associated with maternal and children’s glucose metabolism—a longitudinal study

Table 2 Associations between children’s LTL with maternal and newborn characteristics

	Model 0			Model 1			Model 2			Model 3
	Beta	SE	P	Beta	SE	P	Beta	SE	P	Beta	SE	P
Maternal HbA1c (%)	−0.061	0.047	0.191	−0.018	0.017	0.272	−0.017	0.017	0.307	−0.03	0.017	0.08
Maternal FBG (mmol/L)	0.121	0.048	0.012	0.046	0.016	0.004	0.042	0.016	0.009	0.034	0.016	0.035
Maternal glucose 60 (mmol/L)	0.021	0.01	0.035	0.031	0.016	0.058	0.028	0.016	0.08	0.017	0.016	0.29
Maternal glucose 120 (mmol/L)	0.032	0.012	0.008	0.038	0.016	0.018	0.036	0.016	0.025	0.026	0.016	0.106
Maternal OGTT GAUC	0.019	0.007	0.01	0.035	0.016	0.028	0.034	0.016	0.037	0.023	0.016	0.151
Maternal GDM (IADPSG) (%)	0.085	0.046	0.063	−0.025	0.016	0.113	−0.016	0.016	0.331	−0.018	0.016	0.255

Model 0: unadjusted; Model 1 (basic): adjusted for children’s sex and age
Model 2 (perinatal and children’s environmental factors): Model 1 + C-section or not, history of breast feeding, children’s BMI and exercise level (0, 1, 2)
Model 3 (parental and newborn effects): Model 2 + maternal prepregnant BMI, maternal age at EDC, parity, birthweight and current mother and father diabetes or not

ISSN: 1741-7015