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Fig. 1 | BMC Medicine

Fig. 1

From: Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study

Fig. 1

Schematic overview of the study. A The analysis scheme for the association analysis between the 3 branched amino acids (BCAAs) and 537 cardiometabolic disease (CMD) parameters, which are grouped into the nine categories indicated at the bottom of the panel. The number of the parameters per category is shown in parentheses. B The bi-directional Mendelian randomization analysis scheme. The causal relationship from BCAAs to CMD parameters is shown by the blue arrow and the causal relationship from CMD parameters to BCAAs is shown using red arrows. The impact of confounding factors such as BMI is shown by gray arrows

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