Fig. 4

Performance of the ACEPLY model on DFS. A Kaplan–Meier curve of high- and low-risk group of stage I patients in the validation cohort based on linear prognostic index with a cut-off value derived from the discovery cohort. B Time-dependent area under the curve (AUC) of the prediction model validated in the external cohort. C Model calibration in the validation cohort. D Decision curve analysis of the prediction model. The probability threshold indicates the ratio of benefit of true positives vs. the harm of false positives