Fig. 4

PAE-associated differential gene expression in the placenta. a Volcano plot showing the distribution of associations between mRNA expression and PAE. Horizontal line marks FDR 0.05. b Venn diagram showing the number of PAE-associated differentially expressed genes, which are in common between all PAE placentas and the early PAE subgroup. c Significantly enriched terms identified in GO:BP enrichment analysis of PAE-associated differentially expressed genes in placenta (FDR-corrected q-value < 0.05). The 30 most significant pathways are shown. Control n = 41, PAE n = 64, and early PAE n = 23