Starch intake, amylase gene copy number variation, plasma proteins, and risk of cardiovascular disease and mortality

Table 3 Associations between intake of AMY1 copy number and CVD and mortality risk (n = 3932)

	AMY1 copy number				P trend	Continuous^a	P value
	1–4 copies	5–6 copies	7–9 copies	10 and above copies	P trend	Continuous^a	P value
CVD
Cases/non-case	166/668	303/1189	186/788	121/511	-
Age- and sex-adjusted model	1 [reference]	1.03 (0.86, 1.25)	0.98 (0.79, 1.20)	0.99 (0.78, 1.25)	0.75	1.02 (0.99, 1.05)	0.27
CHD
Cases/non-case	90/744	173/1319	99/875	72/560	-
Age- and sex-adjusted model	1 [reference]	1.10 (0.85, 1.42)	0.96 (0.72, 1.27)	1.09 (0.80, 1.48)	0.95	1.03 (0.99, 1.07)	0.17
Ischemic stroke
Cases/non-case	78/756	127/1365	82/892	49/583	-
Age- and sex-adjusted model	1 [reference]	0.93 (0.70, 1.23)	0.92 (0.67, 1.25)	0.83 (0.58, 1.19)	0.33	1.01 (0.96, 1.06)	0.76
All-cause mortality
Cases/non-case	302/532	547/945	361/613	223/409
Age- and sex-adjusted model	1 [reference]	1.03 (0.90, 1.19)	1.04 (0.89, 1.21)	0.96 (0.81, 1.15)	0.77	1.01 (0.99, 1.03)	0.49
CVD mortality
Cases/non-case	91/743	173/1319	99/875	58/574
Age- and sex-adjusted model	1 [reference]	1.08 (0.84, 1.39)	0.94 (0.71, 1.25)	0.83 (0.60, 1.15)	0.16	1.02 (0.98, 1.06)	0.44

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