Table 2 Adjusted incidence rate ratios for atrial fibrillation according to exposure to a bereavement in childhood
Exposure | Death of a parent or a sibling | Death of a parent | Death of a siblinga | ||||
|---|---|---|---|---|---|---|---|
Events/person-years | Model 1 IRR (95% CI)b | Model 2 IRR (95% CI)c | Events/person-years | Model 2 IRR (95% CI)c | Events/person-years | Model 2 IRR (95% CI)c | |
Unexposed | 7158/127,901,121 | 1.00 | 1.00 | 7356/129,284,682 | 1.00 | 7919/126,530,901 | 1.00 |
Any loss in childhood | 615/4,409,805 | 1.26 (1.16–1.37) | 1.24 (1.14–1.35) | 473/3,210,311 | 1.25 (1.14–1.37) | 158/1,279,249 | 1.18 (1.01–1.38) |
Cause of deathd | |||||||
Death due to CVD | 143/604,057 | 1.96 (1.66–2.32) | 1.93 (1.64–2.28) | 141/581,394 | 1.95 (1.65–2.31) | 6/33,493 | 1.62 (0.73–3.62) |
Other natural deaths | 310/2,349,870 | 1.19 (1.07–1.34) | 1.17 (1.05–1.32) | 218/1,574,633 | 1.14 (0.99–1.30) | 97/808,789 | 1.21 (0.99–1.48) |
Unnatural death | 158/1,435,306 | 1.03 (0.88–1.21) | 1.02 (0.87–1.19) | 111/1,040,552 | 0.98 (0.81–1.19) | 54/429,692 | 1.09 (0.84–1.43) |
Age of offspring at the time of loss (in years) | |||||||
0–5 | 139/1,451,840 | 1.24 (1.05–1.47) | 1.22 (1.03–1.44) | 77/840,906 | 1.16 (0.92–1.46) | 62/619,952 | 1.23 (0.96–1.58) |
6–12 | 221/1,596,481 | 1.31 (1.14–1.50) | 1.29 (1.12–1.47) | 173/1,210,311 | 1.31 (1.13–1.53) | 55/415,036 | 1.21 (0.93–1.58) |
13–18 | 255/1,361,484 | 1.24 (1.09–1.40) | 1.22 (1.07–1.38) | 223/1,159,094 | 1.24 (1.08–1.41) | 41/244,262 | 1.07 (0.79–1.46) |
Sex of the deceased parent | |||||||
Mother | NA | NA | NA | 110/967,799 | 0.94 (0.78–1.14) | NA | NA |
Father | NA | NA | NA | 363/2,242,512 | 1.39 (1.24–1.54) | NA | NA |