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Table 3 Characteristic of 1108 NSCLC patients with ICI from Nanfang Hospital cohort

From: Interstitial pneumonitis associated with combined regimen of immunotherapy and conventional therapies—pharmacovigilance database analysis with real-world data validation

Variables

ICI-combined therapy, N = 956(%)

ICI monotherapy, N = 152(%)

P-value

Age

61.4

61.5

 

Sex

  

0.67

 Female

239 (25.0)

41 (27.0)

 

 Male

717 (75.0)

111 (73.0)

 

Clinical Stage (AJCC 8th edition)

  

0.002

 I–III

274 (28.7)

25 (16.4)

 

 IV

682 (71.3)

127 (83.6)

 

Smoking status

  

0.220

 Ever smoking

590 (61.7)

84 (55.3)

 

 Never smoking

315 (33.0)

61 (40.1)

 

 Unknown

51 (5.3)

7 (4.6)

 

Pathology subtypes

  

0.725

 Squamous cell carcinoma

337 (35.3)

50 (32.9)

 

 Adenocarcinoma

506 (52.9)

81 (53.3)

 

 Others

113 (11.8)

21 (13.8)

 

IP

  

0.065

 With IP

75 (7.8)

5 (3.3)

 

 Without IP

881 (92.2)

147 (96.7)

 
  1. IP Interstitial pneumonitis
  2. P < 0.05 indicates a significant difference