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Table 1 Characteristics of the study population by faecal haemoglobin concentration

From: Faecal haemoglobin concentrations are associated with all-cause mortality and cause of death in colorectal cancer screening

Faecal haemoglobin concentration (μg Hb/g faeces)

 

≤7.0 (n=1,044,931)

7.1–11.9 (n=70,168)

12.0–19.9 (n=28,457)

20.0–59.9 (n=43,622)

≥60.0 (n=41,187)

Total (n=1,228,365)

 

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

Sex

 Female

575,530 (55.1)

36,866 (52.5)

13,943 (49.0)

20,211 (46.3)

17,453 (42.4)

664,033 (54.1)

 Male

469,401 (44.9)

33,302 (47.5)

14,514 (51.0)

23,411 (53.7)

23,734 (57.6)

564,362 (45.9)

Age group

 50–55 years

280,312 (26.8)

19,013 (27.1)

5145 (18.1)

7335 (16.8)

6522 (15.8)

318,327 (25.9)

 55–60 years

186,618 (17.9)

10,168 (14.5)

4145 (14.6)

5962 (13.7)

5433 (13.2)

212,326 (17.3)

 60–65 years

184,096 (17.6)

11,129 (15.9)

5009 (17.6)

7674 (17.6)

7154 (17.4)

215,062 (17.5)

 65–70 years

189,363 (18.1)

12,640 (18.0)

6069 (21.3)

9583 (22.0)

9141 (22.2)

226,796 (18.5)

 70–75 years

204,542 (19.6)

17,218 (24.5)

8089 (28.4)

13,068 (30.0)

12,937 (31.4)

225,853 (20.8)

GI bleedings at baseline

 Yes

41,655 (4.0)

3466 (4.9)

1769 (6.2)

2732 (6.3)

2749 (6.7)

52,381 (4.3)

 No

1,003,266 (96.0)

66,702 (95.1)

26,688 (93.8)

40,890 (93.7)

38,438 (93.3)

1,175,984 (95.7)

Prescription medication

 Yes

525,339 (50.3)

34,709 (49.5)

17,104 (60.1)

26,198 (60.1)

24,302 (59.0)

627,652 (51.1)

 No

519,592 (49.7)

35,459 (50.5)

11,353 (39.9)

17,424 (39.9)

16,885 (41.0)

600,713 (48.9)

Educational level

 Elementary school

243,671 (23.3)

19,219 (27.4)

8096 (28.5)

12,502 (28.7)

12,066 (29.3)

295,554 (24.1)

 Vocational/high school

474,709 (45.4)

32,477 (46.3)

13,350 (46.9)

20,440 (46.9)

19,522 (47.4)

560,498 (45.6)

 Short-medium education

248,235 (23.8)

14,529 (20.7)

5474 (19.2)

8370 (19.2)

7517 (18.3)

284,125 (23.1)

 Long education

78,316 (7.5)

3943 (5.6)

1537 (5.4)

2310 (5.3)

2082 (5.1)

88,188 (7.2)

Income quartiles

 1st quantile

247,069 (23.6)

20,339 (29.0)

8955 (31.5)

13,793 (31.6)

13,822 (33.6)

303,978 (24.7)

 2nd quantile

259,463 (24.8)

18,725 (26.7)

7176 (25.2)

11,141 (25.5)

10,468 (25.4)

306,973 (25.0)

 3rd quantile

266,208 (25.5)

16,883 (24.1)

6456 (22.7)

9770 (22.4)

8961 (21.8)

308,278 (25.1)

 4th quantile

272,191 (26.1)

14,211 (20.2)

5870 (20.6)

8918 (20.4)

7936 (19.3)

309,136 (25.2)

History of respiratory disease

 Yes

47,928 (4.6)

3446 (4.9)

1435 (5.0)

2189 (5.0)

1912 (4.6)

56,910 (4.6)

 No

997,003 (95.4)

66,722 (95.1)

27,022 (95.0)

41,433 (95.0)

39,275 (95.4)

1,171,455 (95.4)

History of diabetes

 Yes

35,252 (3.4)

2999 (4.3)

1557 (5.5)

2315 (5.3)

2165 (5.3)

44,288 (3.6)

 No

1,009,679 (96.6)

67,169 (95.7)

26,900 (94.5)

41,307 (94.7)

39,022 (94.7)

1,184,077 (96.4)

History of cardiovascular disease

 Yes

322,509 (30.9)

24,919 (35.5)

11,475 (40.3)

17,815 (40.8)

17,031 (41.4)

393,749 (32.1)

 No

722,422 (69.1)

45,249 (64.5)

16,982 (59.7)

25,807 (59.2)

24,156 (58.7)

834,616 (67.9)

History of other cancers

 Yes

96,989 (9.3)

7067 (10.1)

3505 (12.3)

5560 (12.7)

5261 (12.8)

118,382 (9.6)

 No

947,942 (90.7)

63,101 (89.9)

24,952 (87.7)

38,062 (87.3)

35,926 (87.2)

1,109,983 (90.4)

History of colorectal cancer

 Yes

4112 (0.4)

354 (0.5)

189 (0.7)

317 (0.7)

379 (0.9)

5351 (0.4)

 No

1,040,819 (99.6)

69,814 (99.5)

28,268 (99.3)

43,305 (99.3)

40,808 (99.1)

1,223,014 (99.6)

Charlson Comorbidity Index score

 0

856,810 (82.0)

55,625 (79.3)

21,188 (74.5)

32,352 (74.2)

30,201 (73.3)

996,176 (81.1)

 1

66,437 (6.4)

5186 (7.4)

2597 (9.1)

3745 (8.6)

3498 (8.5)

81,463 (6.6)

 >2

121,684 (11.6)

9357 (13.33)

4672 (16.4)

7525 (17.3)

7488 (18.2)

150,726 (12.3)

  1. Abbreviations: f-Hb faecal haemoglobin concentration, Hb haemoglobin, CRC colorectal cancer, GI gastrointestinal