Table 2 Significant alterations within the microbiome following treatment with chemotherapy

Eggerthella_lenta

Actinobacteria

−2213.24^a

0.0249

1705.20

0.1979

Ruminococcus_sp_5_1_39BFAA

Firmicutes

−1991.78

0.0467

1709.31

0.0566

Coprococcus_eutactus

Firmicutes

−1408.99

0.0390

531.38

0.6447

Eubacterium_limosum

Firmicutes

−1345.83

0.0196

379.88

0.7068

Dorea_longicatena

Firmicutes

−539.86

0.0330

179.41

0.6605

Eubacterium_ventriosum

Firmicutes

−387.33

0.0405

4.52

0.7699

Eubacterium_rectale

Firmicutes

−385.76

0.0489

101.99

0.0477

Ruminococcus_obeum

Firmicutes

−335.56

0.0203

−66.32

0.5297

Eubacterium_hallii

Firmicutes

−321.98

0.0222

86.83

0.4395

Ruminococcus_bromii

Firmicutes

−310.81

0.0381

140.90

0.1650

Ruminococcus_lactaris

Firmicutes

−262.81

0.0443

175.58

0.0408

Dorea_formicigenerans

Firmicutes

−205.70

0.0243

−6.20

0.9005

Faecalibacterium_prausnitzii

Firmicutes

−197.37

0.0244

107.52

0.0273

Bifidobacterium_longum

Actinobacteria

−145.04

0.0475

43.72

0.4658

Pseudoflavonifractor_capillosus

Firmicutes

−142.70

0.0135

7.25

0.7236

Lachnospiraceae_bacterium_2_1_58FAA

Firmicutes

−123.40

0.0240

51.78

0.4341

Clostridium_nexile

Firmicutes

−103.86

0.0287

25.12

0.4864

Anaerostipes_hadrus

Firmicutes

−98.86

0.0328

68.35

0.0359

Holdemania_filiformis

Firmicutes

−96.75

0.0130

18.54

0.6626

Lachnospiraceae_bacterium_1_4_56FAA

Firmicutes

−93.18

0.0084

−20.09

0.6968

Oscillibacter_sp_KLE_1745

Firmicutes

−92.72

0.0113

0.57

0.8362

Clostridium_difficile

Firmicutes

−90.63

0.0037

62.75

0.0379

Erysipelotrichaceae_bacterium_6_1_45

Firmicutes

−88.91

0.0279

20.27

0.6309

Bifidobacterium_pseudocatenulatum

Actinobacteria

−88.90

0.0090

76.46

0.2646

Eubacterium_ramulus

Firmicutes

−87.12

0.0272

−1.07

0.9814

Anaerotruncus_colihominis

Firmicutes

−76.52

0.0263

125.05

0.0335

Bacteroides_fragilis

Bacteroidetes

−72.47

0.0398

−617.32

0.0338

Lachnospiraceae_bacterium_1_1_57FAA

Firmicutes

−66.19

0.0224

−17.52

0.7283

Clostridium_clostridioforme

Firmicutes

−54.17

0.0158

41.60

0.2429

Anaerostipes_caccae

Firmicutes

−51.00

0.0485

71.93

0.2595

Clostridium_citroniae

Firmicutes

−48.79

0.0116

29.33

0.2610

Clostridium_bolteae

Firmicutes

53.47

0.0243

−5.21

0.3687

Clostridium_asparagiforme

Firmicutes

69.40

0.0471

35.90

0.4319

Bacteroides_coprocola

Bacteroidetes

73.82

0.0325

111.77

0.1583

Bacteroides_clarus

Bacteroidetes

78.20

0.0339

54.37

0.5244

Ruminococcus_gnavus

Firmicutes

98.14

0.0405

1.24

0.3913

Clostridium_hathewayi

Firmicutes

99.15

0.0445

−58.06

0.3724

Bacteroides_caccae

Bacteroidetes

101.28

0.0422

36.38

0.6709

Bacteroides_barnesiae

Bacteroidetes

104.08

0.0410

24.30

0.8197

Bacteroides_ovatus

Bacteroidetes

106.44

0.0466

−21.12

0.6440

Bacteroides_uniformis

Bacteroidetes

113.81

0.0313

197.86

0.0284

Bacteroides_dorei

Bacteroidetes

123.27

0.0439

−0.92

0.9919

Roseburia_intestinalis

Firmicutes

162.79

0.0119

28.78

0.1766

Ruminococcus_torques

Firmicutes

167.92

0.0322

116.36

0.0123

Bacteroides_finegoldii

Bacteroidetes

195.39

0.0330

116.89

0.0382

Clostridium_scindens

Firmicutes

268.08

0.0411

−58.14

0.6986

Bacteroides_pectinophilus

Bacteroidetes

383.29

0.0298

−93.49

0.4232

Bacteroides_intestinalis

Bacteroidetes

50.43

0.7363

−243.28

0.0430

Clostridium_sp_ATCC_BAA_442

Firmicutes

134.56

0.2143

−234.69

0.0210

Bifidobacterium_adolescentis

Actinobacteria

115.36

0.3852

−158.22

0.0241

Bacteroides_vulgatus

Bacteroidetes

14.74

0.7399

−78.56

0.0368

Clostridium_symbiosum

Firmicutes

12.47

0.6194

108.89

0.0333

Ruminococcus_callidus

Firmicutes

−80.75

0.3205

199.02

0.0322