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Table 2 Therapeutic strategy during first-line therapy for mBC disease

From: Association between progression-free survival and overall survival in women receiving first-line treatment for metastatic breast cancer: evidence from the ESME real-world database

 

HR + /HER2 − (N = 13,283)

TN

(N = 2845)

HR + /HER2 + (N = 2502)

HR − /HER2 + 

(N = 1403)

Total (N = 20,033)

Chemotherapy only

1631 (12.3%)

1804 (63.4%)

84 (3.4%)

75 (5.3%)

3594 (17.9%)

Targeted therapy only

8 (0.1%)

6 (0.2%)

53 (2.1%)

116 (8.3%)

183 (0.9%)

Endocrine therapy only

5545 (41.7%)

39 (1.4%)

342 (13.7%)

7 (0.5%)

5933 (29.6%)

Chemotherapy and endocrine therapy

3383 (25.5%)

46 (1.6%)

85 (3.4%)

3 (0.2%)

3517 (17.6%)

Chemotherapy and targeted therapy

699 (5.3%)

921 (32.4%)

674 (26.9%)

1164 (83.0%)

3458 (17.3%)

Chemotherapy, targeted therapy and endocrine therapy

1518 (11.4%)

15 (0.5%)

1036 (41.4%)

33 (2.4%)

2602 (13.0%)

Endocrine therapy and targeted therapy

492 (3.7%)

1 (0.0%)

228 (9.1%)

5 (0.4%)

726 (3.6%)

Immunotherapy-based regimen

6 (0.0%)

13 (0.5%)

0 (0.0%)

0 (0.0%)

19 (0.1%)

Other therapy

1 (0.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

1 (0.0%)

  1. Abbreviations: mBC, metastatic breast cancer; HR + , presence of hormone receptor; HR − , absence of hormone receptor; HER2 + , human epidermal growth factor receptor 2 (HER2) protein overexpression; HER2 − , no HER2 protein overexpression; TN, triple negative