Fig. 2

Associations between age at menarche in combination with age at menopause and reproductive span and the risk of cardiovascular events. HR, hazard ratio adjusted for cardiovascular risk factors (income, smoking, alcohol consumption, regular exercise, body mass index, systolic blood pressure, total cholesterol, fasting glucose, hypertension, diabetes mellitus, and dyslipidemia) and reproductive factors (parity, duration of breast feeding, duration of hormone replacement therapy, and duration of oral contraceptive use); CI, confidence interval, a) the association of combined reproductive factors with myocardial infarction. b) the association of combined reproductive factors with ischemic stroke