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Fig. 6 | BMC Medicine

Fig. 6

From: Monocyte, neutrophil, and whole blood transcriptome dynamics following ischemic stroke

Fig. 6

Distinctive profiles of gene expression over time after IS based on self-organizing maps (SOM). DEG profiles are shown across time points in monocytes, neutrophils, and whole blood. Dots on each profile represent 0 (VRFC), 0–24 h, 24–48 h, and >48 h time points from left to right. Rows show similar expression profiles across sample types. The top significant Gene Ontology (GO) terms for biological processes are shown. Color corresponds to the percentage of genes in the GO group present in the profiles. Abbreviations: clust.: clustering; endocardial to mesenchymal transition: endocardial cushion to mesenchymal transition; intracell.: intracellular; mol.: molecular; morphog.: morphogenesis; neg.: negative; pos.: positive; prod.: production; prolif.: proliferation; reg.: regulation; reg. of Cdc42 protein signal: regulation of Cdc42 protein signal transduction; reg. of sk. muscle contraction by Ca2+: regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; res.: response; sig.: signaling

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