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Table 1 Baseline characteristics of the patients enrolled in the study

From: SGLT-2 inhibitors and in-stent restenosis-related events after acute myocardial infarction: an observational study in patients with type 2 diabetes

Variable

SGLT-2i treated patients (n = 177)

Never SGLT-2i users (n = 200)

p-value

Age (years)

66.2 ± 6.3

65.4 ± 6.1

0.416

BMI (kg/m2)

28.2 ± 2.2

28.0 ± 1.8

0.887

Male, n (%)

115 (65.0)

128 (64)

0.465

STEMI, n (%)

99 (55.9)

111 (55.5)

0.245

Diabetes duration, (years)

15.4 ± 3.2

14.9 ± 3.4

0.224

Hypertension, n (%)

97 (54.8)

110 (55.0)

0.526

Dyslipidemia, n (%)

70 (39.5)

73 (36.5)

0.595

Previous CVD, n (%)

58 (32.8)

63 (31.5)

0.439

Smokers, n (%)

29 (16.4)

33 (16.5)

0.544

Retinopathy, n (%)

30 (16.9)

34 (17.0)

0.437

Neuropathy, n (%)

37 (20.9)

41 (20.5)

0.511

Admission therapy

 Metformin, n (%)

106 (59.5)

119 (59.9)

0.512

 DPP-IV inhibitors, n (%)

44 (24.9)

50 (25.0)

0.535

 GLP-1 agonists, n (%)

19 (10.7)

22 (11.0)

0.504

 Sulfonylureas, n (%)

37 (20.9)

42 (21.0)

0.442

 Thiazolidinediones, n (%)

8 (4.5)

10 (5.0)

0.511

 Insulin, n (%)

53 (29.9)

61 (30.5)

0.451

 Multiple glucose-lowering drugs, n (%)

162 (91.5)

184 (92.0)

0.507

 ACE inhibitors, n (%)

53 (29.9)

57 (28.5)

0.254

 ARBs, n (%)

36 (20.3)

38 (19.0)

0.421

 Beta-blockers, n (%)

62 (35.0)

74 (37.0)

0.386

 Diuretics, n (%)

18 (10.2)

21 (10.5)

0.167

 Calcium channel blockers, n (%)

10 (5.6)

12 (6.0)

0.305

 Antiplatelet drugs, n (%)

117 (66.7)

134 (67.0)

0.466

 Heparin, n (%)

6 (3.4)

8 (4.0)

0.397

 Statin, n (%)

120 (67.8)

139 (69.5)

0.336

 Systolic blood pressure (mmHg)

124.1 ± 8.6

124.0 ± 12.2

0.885

 Diastolic blood pressure (mmHg)

78.6 ± 6.3

78.3 ± 6.3

0.587

 Heart rate

83.5 ± 8.9

84.6 ± 10.5

0.587

 Hba1c baseline

6.5 ± 1.6

6.3 ± 1.7

0.295

 HbA1c 3 months

6.6 ± 0.7

6.6 ± 0.7

0.29

 HbA1c 6 months

6.6 ± 0.7

6.6 ± 0.7

0.17

 HbA1c 9 months

8.2 ± 1.2

8.1 ± 1.3

0.168

 HbA1c 12 months

6.8 ± 0.7

6.9 ± 1.3

0.987

 HbA1c 1-year mean

6.8 ± 0.5

6.9 ± 0.6

0.987

 Total cholesterol (mg/dL)

179.6 ± 22.4

182.7 ± 15.3

0.764

 LDL cholesterol (mg/dL)

104.5 ± 31.1

106.9 ± 18.1

0.763

 HDL cholesterol (mg/dL)

39.9 ± 3.9

39.5 ± 3.5

0.596

 Triglycerides (mg/dL)

183.4 ± 20.8

181.6 ± 24.1

0.594

 Creatinine (mg/dL)

1.0 ± 0.1

1.0 ± 0.2

0.65

 CK-MB (IU/L)

128.0 ± 7.9

127.9 ± 9.2

0.638

 Troponin (ng/L)

37.4 ± 3.5

37.7 ± 3.6

0.129

 NT-proBNP (pg/mL)

20696.0 ± 2119.7

20605.0 ± 2370.2

0.125

 CRP (mg/dL)

14.8 ± 1.4

14.7 ± 1.3

0.124

 Glucose (mg/dL)

150.6 ± 54.0

157.0 ± 51.7

0.133

 Stenosis (%)

69.3 ± 5.9

69.8 ± 6.0

0.353

 MLD (mm)

1.1 ± 0.2

1.1 ± 0.1

0.282

 Post-stent MLD (mm)

2.5 ± 0.4

2.5 ± 0.3

0.441

 Lesion length

21.4 ± 1.9

21.3 ± 2.1

0.368

 Ref diameter

2.8 ± 0.4

2.8 ± 0.2

0.279

  1. Data are presented as mean ± SD
  2. BMI Body mass index, HbA1c Glycated hemoglobin, CK-MB Creatine phosphokinase-MB, CRP C-reactive protein, MLD Minimum lumen diameter