Vaginal and neonatal microbiota in pregnant women with preterm premature rupture of membranes and consecutive early onset neonatal sepsis

Table 3 Bacterial taxa differentially distributed in the vaginal microbiota of EONS and non-EONS cases

Bacterial taxa	V2		V2m		V2l
Bacterial taxa	Mann–Whitney test	Fisher’s exact test	Mann–Whitney test	Fisher’s exact test	Mann–Whitney test	Fisher’s exact test
Enterococcus faecalis^a	0.0081	0.0256	0.0133	0.0098	ns	0.0306
Escherichia/Shigella^a	ns	ns	0.0375	NA	0.0225	ns
Facklamia^a	0.0037	0.0105	0.0014	0.0045	0.0335	ns
Winkia neuii^a	ns	ns	0.0111	0.0314	0.0114	0.0172
Anaerococcus obesiensis^b	0.0394	ns	0.0418	ns	0.0365	ns
Anaerococcus lactolyticus^b	0.0440	ns	ns	ns	ns	ns
Howardella^b	0.0122	0.0135	ns	ns	0.0454	ns
Staphylococcus aureus^a	0.0011	0.0073	0.0064	0.0201	0.0335	ns
Campylobacter ureolyticus^b	0.0336	ns	ns	ns	NA	NA
Eremecoccus^a	NA	NA	0.0064	0.0201	NA	NA
Uncl. Streptococcus^a	ns	ns	0.0363	ns	ns	ns
Lactobacillus iners^a	ns	0.0349	ns	ns	0.0449	0.0306

Uncorrected p-values are given
V2, all samples collected prior to delivery; V2M, vaginal samples from mothers with > 2 days of antibiotic treatment; V2l, vaginal samples from mothers with > 6 days of antibiotic treatment; ns, not significant (p > 0.05); NA, taxon present in < 10% of samples
^aProbable bacterial risk taxa (more abundant in EONs cases)
^bProbable protective bacterial taxa (more abundant in non-EONs cases)

ISSN: 1741-7015