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Table 2 The BP, LV structure, and function in different BW and GA groups

From: The association of gestational age and birthweight with blood pressure, cardiac structure, and function in 4 years old: a prospective birth cohort study

 

LBW (n = 45)

NBW (n = 826)

Macrosomia (n = 72)

P value

Preterm (n = 81)

Term (n = 862)

P value

Total

(n = 943)

Blood pressure

 SBP, mean (SD), mmHg

98.93 (7.93)

98.16 (7.67)

100.22 (7.24)

0.09

98.24 (8.17)

97.54 (7.72)

0.80

97.57 (7.72)

 DBP, mean (SD), mmHg

57.63 (7.35)

57.46 (6.27)

57.20 (6.45)

0.94

57.72 (6.37)

57.04 (6.32)

0.89

57.04 (6.19)

 MAP, mean (SD), mmHg

72.24 (6.65)

71.45 (5.98)

71.59 (5.61)

0.69

71.88 (6.55)

70.89 (5.99)

0.17

70.97 (5.95)

LV structure

 IVSd, mean (SD), mm

3.88 (0.63)

3.84 (0.53)

3.82 (0.31)

0.88

3.79 (0.33)

3.81 (0.59)

0.80

3.79 (0.56)

 LVIDd, mean (SD), mm

34.92 (2.44)

35.75 (2.55)

36.78 (2.20)a,b

0.001

35.52 (2.72)

35.48 (2.53)

0.89

35.47 (2.51)

 LVPWd, mean (SD), mm

4.02 (0.51)

4.14 (0.61)

4.22 (0.47)

0.28

4.15 (0.63)

4.15 (0.59)

10.00

4.14 (0.56)

 IVSs, mean (SD), mm

6.46 (0.86)

6.53 (0.98)

6.93 (0.93)a

0.006

6.53 (0.88)

6.57 (0.97)

0.78

6.57 (0.95)

 LVIDs, mean (SD), mm

22.20 (1.78)

22.81 (1.97)

23.43 (2.10)a,b

0.01

22.69 (1.94)

22.57 (1.96)

0.63

22.57 (1.94)

 LVPWs, mean (SD), mm

7.82 (0.93)

7.80 (0.99)

8.03 (0.95)

0.18

7.85 (0.90)

7.87 (0.95)

0.84

7.84 (0.91)

 RWT

0.23 (0.04)

0.23 (0.04)

0.22 (0.02)

0.35

0.23 (0.03)

0.23 (0.04)

0.92

0.20 (0.10)

 LVM, mean (SD), g

30.44 (4.66)

32.34 (6.38)

34.47 (5.55)a,b

0.006

31.62 (5.09)

31.83 (6.33)

0.79

31.66 (6.04)

 LVMI, mean (SD), g/m2.7

25.58 (3.57)

26.19 (4.83)

26.30 (3.74)

0.75

25.73 (4.03)

26.34 (4.97)

0.32

26.20 (4.74)

 cIMT, mean (SD), *10−2mm

41.35 (4.84)

40.45 (4.58)

40.82 (4.59)

0.58

40.88 (4.76)

40.76 (4.81)

0.87

40.78 (4.81)

LV function

 LVEF, mean (SD), %

66.99 (4.27)

69.21 (4.08)

66.93 (4.42)

0.97

66.54 (3.98)

66.93 (4.12)

0.46

66.90 (4.14)

 LVFS, mean (SD), %

36.37 (3.37)

36.17 (3.21)

36.50 (3.49)

0.70

3 6.06 (3.12)

36.36 (3.23)

0.47

36.34 (3.25)

 Tei index, mean (SD), %

44.82 (6.44)

43.77 (7.03)

43.01 (6.17)

0.45

44.20 (7.85)

43.22 (6.27)

0.21

43.26 (6.20)

 E/A

1.78 (0.35)

1.81 (0.36)

1.79 (0.39)

0.71

1.81 (0.30)

1.80 (0.34)

0.79

1.81 (0.40)

 CO, mean (SD), L/min

4.09 (1.01)

4.22 (1.20)

4.55 (1.39)

0.10

4.37 (1.27)

4.19 (1.13)

0.22

4.19 (1.16)

 SV, mean (SD), mL

43.37 (10.32)

46.36 (12.98)

51.13 (14.94)a,b

0.008

47.89 (12.87)

45.70 (12.41)

0.16

45.71 (12.56)

 TPVR, mean (SD), dyne*s/cm5

1540.19 (525.32)

1465.55 (447.13)

1386.20 (491.63)

0.28

1427.89 (455.43)

1463.51 (444.36)

0.54

1469.40 (450.46)

 EDV, mean (SD), %

50.97 (8.80)

53.94 (9.23)

57.65 (8.26)a,b

0.001

53.22 (9.85)

53.00 (8.98)

0.85

52.95 (8.89)

 ESV, mean (SD), %

16.77 (3.50)

17.99 (3.85)

19.22 (4.11)a,b

0.008

17.76 (3.84)

17.52 (3.77)

0.61

17.50 (3.75)

 VTI, mean (SD), cm

21.72 (3.63)

21.50 (3.24)

21.74 (3.93)

0.80

22.31 (3.51)

21.52 (3.25)

0.05

21.57 (3.28)

 GLS, mean (SD), %

23.49 (2.27)

23.57 (2.30)

23.36 (2.33)

0.87

23.39 (2.62)

23.58 (2.28)

0.65

23.54 (2.26)

 Prehypertension, N (%)

4 (8.9%)

131 (15.8%)

6 (8.3%)

0.13

11 (13.6%)

130 (15.1%)

0.09

141 (14.9%)

 Hypertension, N (%)

6 (13.3%)

85 (10.3%)

10 (13.9%)

0.71

11 (13.6%)

89 (10.3%)

0.85

101 (10.7%)

 LVH, N (%)

0 (0.0%)

53 (6.4%)

2 (2.8%)

0.27

2 (2.5%)

53 (6.1%)

0.57

55 (5.8%)

  1. The bold values were P < 0.05
  2. LBW Low birthweight, NBW Normal birthweight, SBP Systolic blood pressure, DBP Diastolic blood pressure, LV Left ventricle, IVSd Ventricle interventricular septal thickness in diastole, LVIDd LV internal diameter in diastole, LVPWd LV posterior wall thickness in diastole, IVSs Ventricle interventricular septal thickness in systole, LVIDs LV internal diameter in systole, LVPWs LV posterior wall thickness in systole, RWT Relative wall thickness, LVM Left ventricle mass, LVMI LV mass index, cIMT carotid artery intima-media thickness, LVEF LV ejection fraction, LVFS LV fractional shorting, CO Cardiac output, SV Stroke volume, TPVR Total peripheral vascular resistance, MAP Mean arterial pressure, EDV End diastolic volume, ESV End systolic volume, VTI Velocity time integral, GLS Global longitudinal strain, LVH LV hypertrophy
  3. aCompared with NBW were significant using Bonferroni test
  4. bCompared with LBW were significant using Bonferroni test