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Fig. 7 | BMC Medicine

Fig. 7

From: The impact of metabolic endotoxaemia on the browning process in human adipocytes

Fig. 7

The Impact of Endotoxin (LPS) on Mitochondrial Biogenesis. Primary human adipocytes were differentiated with or without rosiglitazone (Rosi), 100 ng/mL lipopolysaccharide (LPS100) or a combination of the two. Mitochondrial biogenesis genes DNA polymerase gamma (POLG), nuclear respiratory factor 1 (NRF1) and mitochondrial transcription factor A (TFAM) were measured using RT-PCR, with L19 as a housekeeping control. Data represent mean ± SEM. The two-way ANOVA test was used to test significance; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared to control, † p < 0.05, †† p < 0.01, ††† p < 0.001, †††† p < 0.0001 compared to Rosi treatment, x p < 0.05, xx p < 0.01, xxx p < 0.001, xxxx p < 0.0001 compared to LPS

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