| Lean | Overweight | Obese | Pre-Surgery | Post-Surgery |
---|
n | 44 | 49 | 63 | 26 | 26 |
Age (years) | 32.07 ± 1.2 | 31.56 ± 1.4 | 39.93 ± 1.7***#### | 54.50 ± 3.41 | 54.50 ± 3.41 |
BMI (Kg/m2) | 22.14 ± 0.7 | 27.30 ± 0.8**** | 36.35 ± 1.0****#### | 42.21 ± 3.24 | 36.70 ± 3.14++++ |
Glucose (mmol/l) | 3.58 ± 0.1 | 3.63 ± 0.1 | 5.92 ± 0.4****#### | 9.22 ± 1.57 | 6.96 ± 0.83++++ |
LDL (mmol/l) | 4.56 ± 0.2 | 4.46 ± 0.2 | 3.82 ± 0.2**# | 3.08 ± 0.54 | 2.67 ± 0.40+ |
HDL (mmol/l) | 1.74 ± 0.1 | 1.53 ± 0.1 | 1.35 ± 0.1**** | 1.08 ± 0.16 | 1.04 ± 0.18 |
TGs (mmol/l) | 3.11 ± 0.2 | 3.26 ± 0.1 | 2.65 ± 0.2# | 1.83 ± 0.65 | 1.39 ± 0.40+ |
Insulin (pmol/l) | 39.79 ± 4.3 | 64.58 ± 6.3* | 62.97 ± 5.9* | 31.90 ± 11.26 | 17.16 ± 5.49++++ |
- Selected pertinent clinical, anthropometric and fasting biochemical characteristics of the study participants based on body mass index (BMI) and bariatric surgery status; participants with (i) BMI: 18.5–24.9 kg/m2, (lean: n = 44); (ii) BMI: 25–29.9 kg/m2 (overweight: n = 49); and (iii) BMI: > 30 kg/m2 (obese: n = 63). Data are presented as mean ± SEM. All samples were taken in a fasted state. One-way ANOVA or the Kruskal–Wallis test were used to test significance between group comparisons; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 for lean vs. overweight and lean vs. obese, # p < 0.05, ## p < 0.01, ### p < 0.001, #### p < 0.0001 for overweight vs. obese. Significant differences between measurements taken pre- and 6 months post-bariatric surgery were assessed using two-tailed paired T-Test or Wilcoxon signed ranks test; +p < 0.05, ++p < 0.01, +++p < 0.001, ++++p < 0.0001
- BMI Body mass index, TGs Triglycerides, LDL Low-density lipoprotein, HDL High-density lipoprotein