Fig. 9From: Statistical analysis of high-dimensional biomedical data: a gentle introduction to analytical goals, common approaches and challengesVisualization of the effect of batch correction. Heatmaps of hierarchical clustering of sponge metagenomics data studying two tissues types (C and E) with 2 batches, before and after Combat batch correction. Without batch correction (top figure), the clustering is mainly driven by the batch effect. After correction, the clustering is driven by the tissue type (bottom figure). Source: [49]Back to article page