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Table 1 Primary series vaccine effectiveness against VOC

From: Real-world effectiveness and factors associated with effectiveness of inactivated SARS-CoV-2 vaccines: a systematic review and meta-regression analysis

VOC

No. of estimates

Pooled estimate (95% CI)

Pooled VE (%) (95% CI)

Against SARS-CoV-2 infection

 Alpha

2

0.280 (0.062, 1.273)

72.0 (− 27.3, 93.8)

 Gamma

7

0.558 (0.514, 0.606)

44.2 (39.4, 48.6)

 Delta

26

0.472 (0.393, 0.567)

52.8 (43.3, 60.7)

 Omicron

9

0.836 (0.772, 0.905)

16.4 (9.5, 22.8)

Against severe COVID-19

 Alpha

5

0.160 (0.059, 0.430)

84.0 (57.0, 94.1)

 Gamma

7

0.267 (0.202, 0.353)

73.3 (64.7, 79.8)

 Delta

31

0.306 (0.254, 0.369)

69.4 (63.1, 74.6)

 Omicron

14

0.340 (0.299, 0.386)

66.0 (61.4, 70.1)