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Table 1 Baseline characteristics of the participants

From: Impact of oral intervention on the oral and overall health of children living with HIV in Cambodia: a randomized controlled trial

Characteristics

All participants

(n = 481)

Group A

Intervention group

(HIV-positive, n = 160)

Group B

Control group

(HIV-positive, n = 168)

Group C

Control group

(HIV-negative, n = 154)

Difference between groups A and B, P-value**

Difference between groups A and C, P-value**

Child’s sex, female, n (%)

222

46.1

78

51.3

80

45.5

64

41.6

0.28

0.09

Child’s age, mean (SD)

10.8

3.0

10.7

3.1

10.9

2.9

10.6

2.9

0.75

0.59

 < 6 years old, n (%)

30

6.2

7

4.4

9

5.4

11

7.1

  

 6–8 years old, n (%)

83

17.3

30

18.8

27

16.1

26

16.9

  

 9–12 years old, n (%)

215

44.7

65

40.6

78

46.4

72

46.8

  

 13–15 years old, n (%)

154

32.0

55

34.4

54

32.1

45.0

29.2

  

Dentition type

        

0.74

0.02

 Permanent teeth, n (%)

189

39.2

71

44.4

69

41.1

49

31.8

  

 Mixed dentition, n (%)

263

54.6

77

48.1

88

52.4

98

63.6

  

 Deciduous teeth, n (%)

30

6.2

12

7.5

11

6.5

7

4.5

  

Child’s overall health status

 Viral load detecteda, n (%)

104

31.7

47

30.9

57

32.4

n/a

n/a

0.86

n/a

 Height for age in z-score, mean (SD)

 − 2.0

1.4

 − 2.0

1.4

 − 1.8

1.4

 − 2.2

1.4

0.51

0.09

 BMI for age in z-score, mean (SD)

 − 0.9

1.2

 − 1.1

1.1

 − 0.9

1.2

 − 0.7

1.4

0.59

0.10

 Overall health-related quality of life, mean (SD)

80.0

10.5

79.8

11.6

80.1

10.2

80.2

9.7

0.90

0.49

Child’s oral hygiene status

 Oral health-related quality of life, mean (SD)

12.0

7.3

11.8

7.6

11.9

7.2

12.2

7.1

0.90

0.62

 Decayed, missing, filled teeth, mean (SD)**

          

 DMFT/dmft (total teeth) (n = 481)

8.0

4.8

8.1

4.8

7.6

5.1

8.2

4.7

0.70

0.23

 Permanent teeth (n = 451)

3.9

3.7

4.0

3.6

4.2

3.7

3.4

3.8

0.71

0.27

 Deciduous teeth (n = 292)

7.1

4.8

7.6

4.6

6.5

5.1

7.3

4.4

0.08

0.46

 Salivary pH, mean (SD)

6.1

0.5

6.0

0.6

6.0

0.6

6.2

0.4

0.35

0.04

 Salivary flow quantity/3 min, mean (SD)

2.7

1.3

2.9

1.3

2.8

1.3

2.2

1.3

0.39

 < 0.01

 Debris index, mean (SD)

2.2

0.7

2.2

0.7

2.1

0.7

2.4

0.7

0.62

0.09

Oral mucosal lesions

 Have oral mucosal lesions

63

13.1

26

16.3

27

16.1

n/a

n/a

0.97

n/a

 Abscess

54

11.2

26

16.3

23

13.7

n/a

n/a

  

 Ulceration

5

1.0

1

0.6

3

1.8

n/a

n/a

  

 Acute necrotizing ulcerative gingivitis

4

0.8

0

0

1

0

n/a

n/a

  

Child’s oral care behavior

 Dental visit within the last 12 months due to pain or trouble with teeth (n = 451), n (%)

99

22.0

41

29.1

34

20.4

24

16.8

0.03

0.01

Frequency of tooth brushing per day (n = 452), n (%)

        

0.15

0.05

 Three times or more

115

25.4

41

27.5

40

25.0

34

23.8

  

 Twice a day

133

29.4

47

31.5

48

30.0

38

26.6

  

 Once a day or less

93

20.5

34

22.8

38

23.8

21

14.7

  

 Never clean teeth

111

24.6

27

18.1

34

21.3

50

35.0

  

Duration of tooth brushing (n = 424), n (%)

        

0.44

0.09

 ≤ 1 min

118

27.8

48

36.7

40

25.4

30

22.2

  

 2 min

99

23.3

25

19.1

37

23.4

37

27.4

  

 ≥ 3 min

207

48.8

58

44.3

81

51.3

68

50.3

  

Caregivers’ support in tooth brushing (n = 439), n (%)

    

0.69

0.04

 Caregivers brushed the children’s teeth or watched/advised while children were brushing

27

6.1

13

9.6

11

6.1

3

2.2

  

 Caregivers never cared about tooth brushing

412

93.8

123

90.4

153

93.3

136

97.8

  

Family wealth index, n (%)

        

0.01

0.01

 Lowest

95

19.8

28

17.5

52

31.0

15

9.9

  

 Highest

93

19.4

41

25.6

21

12.5

31

20.4

  
  1. aChildren in group C were excluded from the total number of participants
  2. **Continuous variables were log transformed. Mann–Whitney U test was used to evaluate nonparametric continuous variables, and the chi-square test was utilized to assess categorical variables
  3. Abbreviations: BMI body mass index, HIV human immunodeficiency virus, SD standard deviation