Skip to main content

Table 1 Baseline characteristics and gastric cancer cases in the three studies

From: Development, validation, and evaluation of a risk assessment tool for personalized screening of gastric cancer in Chinese populations

Variables

CKB development cohort

Changzhou validation cohort

Yangzhou screening program

Total (n = 416,343), no. (%)

Cases (n = 3089), no.

Incidence rate (per 100,000 person-years)

Total (n = 13,982), no. (%)

Cases (n = 329), no.

Incidence rate (per 100,000 person-years)

Total (n = 5348), no. (%)

Cases (n = 49), no.

Detection rate, %

Age at baseline, mean (SD), years

54.29 (9.14)

 

54.27 (8.97)

 

57.54 (8.19)

 

 40–44

83,099 (19.96)

168

19.88

2509 (17.94)

19

55.43

280 (5.24)

0

0.00

 45–49

67,379 (16.18)

236

34.31

2484 (17.77)

31

92.27

708 (13.24)

1

0.14

 50–54

85,415 (20.52)

473

55.00

2827 (20.22)

54

143.38

1178 (22.03)

4

0.34

 55–59

67,407 (16.19)

593

89.01

2518 (18.01)

68

207.45

881 (16.47)

2

0.23

 60–64

47,091 (11.31)

572

125.86

1612 (11.53)

70

341.75

929 (17.37)

13

1.40

 65–69

38,720 (9.30)

570

159.27

1222 (8.74)

58

394.80

1031 (19.28)

21

2.04

 70–75

27,232 (6.54)

477

201.92

810 (5.79)

29

317.33

341 (6.38)

8

2.35

Sex

 Women

244,810 (58.80)

1033

42.20

8010 (57.29)

95

89.38

3132 (58.56)

7

0.22

 Men

171,533 (41.20)

2056

123.87

5972 (42.71)

234

306.53

2216 (41.44)

42

1.90

Education

 College or above

21,145 (5.08)

102

48.71

64 (0.46)

1

119.27

122 (2.28)

0

0.00

 High school

63,402 (15.23)

310

49.18

1269 (9.08)

17

99.52

475 (8.88)

3

0.63

 Middle school

109,701 (26.35)

664

61.01

5432 (38.85)

108

150.00

1628 (30.44)

12

0.74

 Illiterate or primary school

222,095 (53.34)

2013

92.35

7217 (51.62)

203

218.97

3123 (58.40)

34

1.09

BMI, mean (SD)

23.76 (3.39)

 

23.54 (3.35)

 

24.43 (3.04)

 

 ≥ 18.5

398,633 (95.75)

2885

73.16

13,299 (95.12)

312

179.12

5258 (98.32)

46

0.87

 < 18.5

17,710 (4.25)

204

124.26

683 (4.88)

17

201.37

90 (1.68)

3

3.33

Pack-years of smoking

 Never (0 pack-year)

278,156 (66.81)

1389

50.09

9544 (68.26)

160

127.29

3728 (69.71)

18

0.48

 > 0 to < 20 pack-years

55,078 (13.23)

559

104.18

1406 (10.06)

39

212.39

679 (12.70)

15

2.21

 ≥ 20 pack-years

83,109 (19.96)

1141

142.94

3032 (21.69)

130

337.07

941 (17.60)

16

1.70

Alcohol drinking per daya

 Never or light

379,928 (91.25)

2598

69.27

11,218 (80.23)

224

152.40

4716 (88.18)

39

0.83

 Moderate or heavy

36,415 (8.75)

491

137.46

2764 (19.77)

105

294.57

632 (11.82)

10

1.58

Intake of fresh vegetables and fruitsb

 Frequent

113,736 (27.32)

695

61.29

4589 (32.82)

89

146.21

1586 (29.66)

9

0.57

 Occasional

302,607 (72.68)

2394

80.51

9393 (67.18)

240

197.12

3762 (70.34)

40

1.06

Intake of salty foodsc

 Occasional

320,109 (76.89)

2105

66.90

7494 (53.60)

177

181.19

4646 (86.87)

41

0.88

 Frequent

96,234 (23.11)

984

102.37

6488 (46.40)

152

178.95

702 (13.13)

8

1.14

Previous cancer diagnosis

 No

414,227 (99.49)

3042

74.39

13,854 (99.08)

324

178.84

5312 (99.33)

49

0.92

 Yes

2116 (0.51)

47

256.70

128 (0.92)

5

341.60

36 (0.67)

0

0.00

Family history of cancer in first-degree relatives

 No

341,680 (82.07)

2328

69.16

11,121 (79.54)

247

169.73

3556 (66.49)

29

0.82

 Yes

74,663 (17.93)

761

102.60

2861 (20.46)

82

220.99

1792 (33.51)

20

1.12

History of peptic ulcer

 No

399,248 (95.89)

2844

72.19

13,822 (98.86)

321

177.71

4886 (91.36)

44

0.90

 Yes

17,095 (4.11)

245

145.81

160 (1.14)

8

400.69

462 (8.64)

5

1.08

  1. SD Standard deviation, BMI Body mass index, CKB China Kadoorie Biobank
  2. aNever or light alcohol drinking was defined as alcohol intake less than 25 g/day in men and 15 g/day in women in the past year, otherwise was moderate or heavy alcohol drinking
  3. bIn the CKB cohort, frequent intake of fresh vegetables and fruits was defined as eating vegetables every day and fruits ≥ 4 days per week or eating fruits every day and vegetables ≥ 4 days per week, otherwise was occasional. In the Changzhou cohort and Yangzhou screening program, frequent intake was defined as eating vegetables every day and fruits at least 3 days per week or eating fruits every day and vegetables at least 3 days per week, otherwise was occasional
  4. cIn the CKB cohort, frequent intake of salty foods was defined as eating preserved salty vegetables ≥ 4 days per week, otherwise was occasional. In the Changzhou and Yangzhou studies, frequent intake of salty foods was defined as eating preserved salty vegetables at least 3 days per week
Back to article page

BMC Medicine

ISSN: 1741-7015

Contact us